云南勐腊县391例麻风新发病人畸残影响因素分析

目的：分析勐腊县近70年麻风新发患者畸残情况及影响因素。方法：收集勐腊县历年麻风患者资料，采用二元logistic回归分析方法分析麻风畸残的影响因素。结果：共分析勐腊县麻风患者391例，麻风新发病例畸残率46.04%（180/391），其中2 级畸残率44.50%（174/391）。延迟期2～5年、5～10年、≥10年的麻风患者发生畸残风险分别是延迟期＜2年的2.49倍（P=0.018）、4.8倍（P＜0.001）和14.56倍（P＜0.001）；家外传染的麻风畸残风险是家内传染的1.93倍（P=0.030）；有麻风反应的麻风畸残风险是没有反应的2.36倍（P=0.010）；神经损害数2～4条和＞4条的麻风畸残风险分别是神经损害1条的3.37倍（P=0.029）和5.09倍（P=0.009）。结论：勐腊县麻风畸残的危险因素主要有延迟期、家外传染、麻风反应、神经损害数。

Analysis on disability factors of 391 new leprosy cases in Mengla county,Yunnan province

Objective:To analyze disabilities and influencing factors among 391 newly diagnosed leprosy cases in Mengla county,Yunnan province in the past 70 years.Methods:The original data of leprosy patients was collected and the influencing factors of leprosy disabilities were analyzed by binary logistic regression analysis.Results:The disability rate among the 391 leprosy patients was 46.04%(180/391),of which grade-2 disability rate was 44.50%(174/391).The disability risks were 2.491 times,4.8 times and 14.56 times among the patients with delayed periods of 2-5 years,5-10 years and≥10 years when compared to those with a delay<2 years,respectively.The disability risk in the patients with a family history was 1.93 times higher than those without family history(P=0.030).The disability risk among the patients with leprosy reaction was 2.36 times higher than those without leprosy reaction(P=0.010).The disability risks among the patients with more than 2-4 nerve damages or≥4 never damage were 3.67 times(P=0.029)and 5.019 times(P=0.009)than those with one nerve damage,respectively.Conclusion:The main risk factors of leprosy disability in Mengla county were diagnosis delay,with a family history,leprosy reaction and more than 2 nerve damage in the time of diagnosis.