X线联合卡替洛尔治疗婴幼儿血管瘤疗效观察

目的:评价低剂量浅层X线联合卡替洛尔滴眼液治疗婴幼儿血管瘤的疗效及安全性。方法:对我科门诊2017年6月至2018年6月确诊的婴幼儿血管瘤患者予SRT-100 TM放射治疗系统低剂量浅层X线照射,管电压50 KV,剂量150 cGy,1次/周,共3次,结束后外涂卡替洛尔滴眼液,随访1年。结果:完成治疗和随访的患者72例,其中显效56例,好转12例,进步3例,无效1例,有效率为94.4%;不良反应仅两例患儿局部皮肤出现暂时性色素沉着,未见其他不良反应。结论:低剂量浅层X线照射联合卡替洛尔滴眼液外涂治疗婴幼儿血管瘤安全有效。

Efficacy of X-ray irradiation combined with carteolol in the treatment of infantile hemangioma

Objective: To assess the clinical efficacy and safety of low-dose superficial X-ray irradiation combined with carteolol eye drops in the treatment of infantile hemangioma. Methods: The patients from June 2017 to June 2018 were treated with low dose shallow X-ray irradiation of SRT-100^TM radiotherapy system with the tube voltage of 50 KV and dose of 150 cGy, once a week for 3 times. The patients were treated with local carteolol after laser therapy. The patients were followed up for 1 year. Results: Seventy-two cases completed treatment and follow-up. Of 72 patients, 56 were significantly improved, 12 were improved, 3 were less improved, 1 was ineffective, with an effective rate of 94.4%. There was no obvious adverse reaction except temporary skin pigmentation in 2 cases. Conclusion:The therapy of low-dose shallow X-ray irradiation combined with carteolol eye drops is safe and effective in the treatment of infantile hemangioma.