Systo-diastolic ventricular function in patients with hypertension: an echocardiographic tissue doppler
imaging evaluation study |
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Authors: | Massimo Leggio Luca Sgorbini Marco Pugliese Andrea Mazza Maria Grazia Bendini Maria Stella Fera Ezio Giovannini Francesco Leggio |
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Institution: | (1) Cardiovascular Department, Cardiac Rehabilitation Operative Unit (S.I.), San Filippo Neri Hospital, Via della Lucchina 41, Rome, 00135, Italy;(2) Cardiologic-Geriatric Department, Cardiologic Operative Unit, I.N.R.C.A.-I.R.C.C.S. Hospital, Rome, Italy;(3) Cardiovascular Department, 1 Cardiologic Operative Unit, San Camillo-Forlanini Hospital, Rome, Italy;(4) Cardiologic Division, Santa Maria della Stella Hospital, Orvieto, Italy |
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Abstract: | Background Tissue Doppler imaging (TDI) has evolved to become a useful non invasive method that can complement other echocardiographic
techniques in the assessment of left ventricular function in different clinical conditions. Spectral pulsed TDI can provide
measurements of regional systolic and diastolic myocardial velocities and is particularly useful in detecting abnormalities
of left ventricular systolic and diastolic function. We investigated the presence of systo-diastolic dysfunction in patients
(pts) with hypertension compared with pts affected by hypertensive cardiomyopathy and normal control subjects.
Methods We evaluated 214 pts with traditional echocardiography and TDI: 69 normal control subjects (Group A); 145 pts with hypertension,
divided according to base echocardiographic evaluation in 74 with no evidence of hypertensive cardiomyopathy (diastolic dysfunction
and ventricular hypertrophy, Group B), and 71 with evidence of hypertensive cardiomyopathy (Group C). Pts groups were matched
for age, sex, heart rate, smoking status and body surface area.
Results There were no significant differences in ventricular diameters, volumes, shortening and ejection fraction values; TDI showed
a progressive systolic wave peak reduction from Group A to B and from Group B to C. Routinely Doppler diastolic function did
not show any significant difference between Group A and B; TDI showed progressive E wave peak velocity decrease and A wave
peak velocity increase from Group A to B and C and from Group B to C.
Conclusions TDI evaluation showed a ventricular systolic dysfunction in pts with hypertensive cardiomyopathy; in addition, an early mild
systo-diastolic dysfunction was detected in subjects with hypertension but no evidence of hypertensive cardiomyopathy. |
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Keywords: | Hypertension Diastolic function Systolic function Pulsed-wave tissue Doppler echocardiography |
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