| 胎仔宫内生长迟缓孕鼠的药物治疗及其胎盘病理学研究 |
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| 引用本文： | 谷立平,张为远,许为,阎国来. 胎仔宫内生长迟缓孕鼠的药物治疗及其胎盘病理学研究[J]. 吉林大学学报(医学版), 1993, 0(5) |
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| 作者姓名： | 谷立平 张为远 许为 阎国来 |
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| 作者单位： | 白求恩医科大学第二临床学院妇产科(谷立平，张为远，许为)，白求恩医科大学第二临床学院妇产科(阎国来) |
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| 摘 要： | 本研究在用更生霉素建立IUGR动物模型的基础上,应用人参茎叶皂甙、丹参、舒喘灵、硫酸锌和人参蜂王浆对胎仔宫内生长迟缓(IUGR)孕鼠进行治疗。结果表明,各治疗组孕鼠妊娠第20天体重明显高于更生霉素组孕鼠(P<0.01)、IUGR胎仔的发生率明显降低(P<0.01);在胎盘组织学上,胎盘的厚度及迷路层血管和血窦成分,各治疗组不同程度地有别于更生霉素组。并对各药物治疗组IUGR进行了讨论。
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| 关 键 词： | 胎儿宫内生长迟缓/药物疗法 胎盘/病理生理 人参皂甙/治疗应用 |
A Study on medicinal treatment in maternal rats for IUGR of the fetal rats and the placental pathology |
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| Gu Liping.et al. A Study on medicinal treatment in maternal rats for IUGR of the fetal rats and the placental pathology[J]. Journal of Jilin University: Med Ed, 1993, 0(5) |
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| Authors: | Gu Liping.et al |
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| Abstract: | Based on the animal modal of intrauterine growth retardation (IUGR) established using actinomycin, pregnant rats with IUGR were treated with ginsenosides, injectio salviae miltiorrhizae composita, salbutamol, zinc sulfate and ginseng royal jelly. The results indicated that after treatment with these drugs, on the 20th day of gestation, body weight of the pregnant rats with IUGR was obviously increased, and the incidence of IUGR in fetal rats fell obviously. As to the placental thickness and the blood capillary and blood sinus components of the placental labyrinth, each medicinal-treated group varied to various degrees from the actinomycin group. The drugs which are used to treat IUGR were also discussed. |
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| Keywords: | fetal growth retardation (IUGR)/DT placenta/PP ginseng saponins/TU |
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