| 1074名油田职工乙肝病毒感染标志的血清学模式分析 |
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| 引用本文： | 张美喜,张建营,张金鉴,周晓阳,田帧,刘雪兰.1074名油田职工乙肝病毒感染标志的血清学模式分析[J].郑州大学学报(医学版),1991(2). |
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| 作者姓名： | 张美喜 张建营 张金鉴 周晓阳 田帧 刘雪兰 |
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| 作者单位： | 河南医科大学预防医学系流行病学教研室
(张美喜，张建营，张金鉴)，河南石油勘探局卫生防疫站
(周晓阳，田帧)，河南石油勘探局卫生防疫站(刘雪兰) |
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| 摘 要： | 本研究使用酶联免疫吸附试验(ELISA)对1074名石油职工HBV感染的血清学标志进行了检测.结果表明HBsAg、抗-HBs、抗—HBc阳性率和HBV总感染率分别为9.8%、26.2%、14.1%和41.0%,进一步对105例HBsAg阳性者检测HBeAg和抗—HBe,阳性率分别为24.8%和46.7%,对151例抗—HBc,阳性者检测抗—HBc—IgM,阳性率为11.3%.根据HBV三项感染标志(HBsAg、抗—HBs、抗—HBc)的组合,其发现八种不同类型组合的血清学模式.本文对此八种血清学模式的意义进行了评价,以期为乙肝的临床诊断及预防措施的制订提供依据。
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| 关 键 词： | HBV感染标志 感染率 血清学模式 酶联免疫吸附试验(ELISA) |
An analysis of serological model of HBV markers in 1 074 petroleum workers |
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| zhang Meixi,Zhang Jianying,Zhang Jinjian,Zhou Xiaoyang,Tian Zhen,LuiXuelan.An analysis of serological model of HBV markers in 1 074 petroleum workers[J].Journal of Zhengzhou University: Med Sci,1991(2). |
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| Authors: | zhang Meixi Zhang Jianying Zhang Jinjian Zhou Xiaoyang Tian Zhen LuiXuelan |
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| Institution: | zhang Meixi;Zhang Jianying;Zhang Jinjian;Zhou Xiaoyang;Tian Zhen;LuiXuelan Department of Epidemiology Anti - epidemic Station in Henan Petroleum Exploration Bureau |
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| Abstract: | Serum samples were collected from 1074 workers in Henan Petroeum Exploration Bureau, andtested for HBV markers with Enzyme Linked Immunosorbent Assay(ELISA)in 1990. The prevalencerates of HBsAg, anti--HBs, anti--HBc and the infection rate of HBV were 9. 8%, 26. 2%, 14.1%and41. 0%, respectively. HBeAg and anti--HBe positive rates were 24. 8% and 46. 7% in 105 HBsAgpositive subjects, anti--HBc--IgM positive rate was 11. 3% in 151 anti--HBc positive subjects. Ac-cording to the combination of three HBVmarkers(HBsAg, anti--HBS and anti--HBc), it was foundthat eight different combbinations of serological model of HBV markers existed in serum. To providescientific basis for diagnosis and prevevtion of HBV infection,we evaluated the significance of the eightdifferent combinations of the serological model in this study |
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| Keywords: | HBV infection marker prevalence rate serological model Enzyme Linked Immunosorbent Assay(ELISA) |
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