Tei指数用于初步估测冠状动脉狭窄程度的临床研究

目的:检测经冠脉造影确定冠脉狭窄程度患者的Tei指数,并进行统计学分析,探讨其用于估测冠状动脉狭窄程度的临床价值。方法:采用组织多普勒显像技术测量30例正常对照组、30例冠状动脉造影阴性组(狭窄程度<50%)、30例轻度冠状动脉狭窄组(狭窄程度50%～74%)和30例中度冠状动脉病变组(狭窄程度75%～94%)的左心室Tei指数。运用统计学方法,分析Tei值与冠脉狭窄程度之间的相关关系。结果:冠状动脉造影阴性组Tei指数与正常对照组比较差异无统计学意义,轻度、中度冠状动脉狭窄组Tei指数显著高于正常对照组(P<0.05);Tei指数与冠脉病变程度呈正相关(r=0.944)。结论:Tei值与冠状动脉狭窄程度存在明显的相关性,可用于初步估测冠状动脉狭窄的程度。

The preliminary assessment of the coronary stenosis scope by applying the Tei index

Objective：To assess coronary stenosis scope preliminarily by applying TDI Tel index. Methods：Determined the left ventricular Tei index by tissue doppler imaging（TDI）technique of the 30 normal subjects, 30 patients with negative results of coronary arteriography（stenosis〈50 % ）, 30 patients with mild coronary stenosis（stenosis 500%o-74 % ）and 30 patients with mod- erate coronary stenosis（stenosis 75 %- 94 % ）. Results： The left ventricular Tel index in mild and moderate coronary stenosis pa- tient was obviously higher than in the normal subject（P〈0. 05） ,but there is no statistic significance in the difference between normal subject and patient with negative results of coronary arteriography. There was significant correlation between coronary stenosis and Tel index（r=0. 944）. Conclusion：The value of Tel index could be applied to assess the stenosis scope of the coro- nary artery.