| 小儿精神发育迟滞合并癫痫的治疗 |
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| 引用本文： | 刘振寰,潘佩光. 小儿精神发育迟滞合并癫痫的治疗[J]. 中国组织工程研究与临床康复, 2002, 6(9): 1384-1384 |
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| 作者姓名： | 刘振寰 潘佩光 |
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| 作者单位： | Nanhai City Hospital for Women and Children，Nanhai 528200，China |
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| 摘 要： | Inordertoexploreeffectiveapproaches，weselected５２chil－drenwithpoorprognosisaftertreatmentbyantiepilepticdrugsfrom４６６childrenwithmentalretardation（１２２withepilepsy）asourstudysubjects．Guanmaishu（hyoscyamine）wasadministeredasassistanceforepilepsy（EP）treatmentwithanti－EPdrugs．Weob－tainedgoodtherapeuticeffecthereisthereport．１Subjectandmethod１．１Subject５２childrenenteredthestudyincluding３９boysand１３girls．２１childrenaged２～３years，３１aged３～５years．２０caseshadEPfo…
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Improvement of mental retardation plus epilepsy in children following management |
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| LIU Zhen-huan,PAN Pei-guang. Improvement of mental retardation plus epilepsy in children following management[J]. Journal of Clinical Rehabilitative Tissue Engineering Research, 2002, 6(9): 1384-1384 |
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| Authors: | LIU Zhen-huan PAN Pei-guang |
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| Abstract: | Objective To investigate the effective management approaches for mental retardation plus epilepsy in children.Method Sodium valproat[15～ 60 mg/（ kg· day)] or nitrazepam[0.5～ 1 mg/（ kg· day） ] and guanmaishu containing hyoscyamine(0.0045～ 0.045 mg/（ kg· day)] as adjuvant were administered for 1.5～2 consecutive years.EEG,three dimensional Doppler ultrasonic examination of cerebral vessels were performed.Result Favorable therapeutic effect was obtained in 25 cases(48.1％ ),good effect in 12 cases(23.1％ ).Conclusion Favorable therapeutic effect of hyoscyamine in epilepsy is correlated with improved cerebral microcirculation,cortical choline receptor blocking ,reduced conduction between synapses.These factors all inhibit onset of epilepsy. |
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| Keywords: | mental retardation epilepsy management hyoscyamine microciculat ion |
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