| 肝细胞癌细胞外基质的分布形式及其临床意义 |
| |
| 引用本文： | 付员根,黄致治.肝细胞癌细胞外基质的分布形式及其临床意义[J].临床与实验病理学杂志,1997,13(3):200-202,I017. |
| |
| 作者姓名： | 付员根 黄致治 |
| |
| 作者单位： | 汕头大学医学院病理学教研室，广东省妇幼保健院 |
| |
| 摘 要： | 目的：了解细胞外基质在肝细胞癌的分布形式；探讨其与肝细胞癌恶性程度的关系。方法：用５种细胞外基质抗体对４０例肝细胞癌作免疫组化染色。结果：显示４种分布形式：连续梁周腺泡型、断续梁周腺泡周型、血管间质型、胞膜胞浆型。前３型与肿瘤生长方式、细胞分化和增殖密切相关。结论：提示细胞外基质在评价肝细胞癌的恶性程度是有用的标志物。
|
| 关 键 词： | 细胞外基质 肝肿瘤 细胞癌 免疫组织化学 |
Distribution patterns of extracellular matrix in hepatocellular carcinoma and its clinical signification |
| |
| Fu Yuangen,Huang Zhizhi,Liang Yingrui,et al.Distribution patterns of extracellular matrix in hepatocellular carcinoma and its clinical signification[J].Chinese Journal of Clinical and Experimental Pathology,1997,13(3):200-202,I017. |
| |
| Authors: | Fu Yuangen Huang Zhizhi Liang Yingrui |
| |
| Abstract: | Purpose In order to find out the distribution patterns of extracellular matrix (ECM) in hepatocellular carcinoma (HCC) and explore the relationship between distribution patterns and hepatocellular carcinoma malignancy. Methods Forty cases of HCC were studied by immunohistochemistry with 5 antibodies of anti ECM. Results Four types of distribution patterns were found: (1) Continuous peritrabecular or periacinar type, (2) Discontinuous peritrabecular or periacinar type, (3) Vascular stroma type, (4) Membrane and cytoplasmic type. The former 3 types were correlated closely with the growth pattern, cell differentiation and proliferation of tumor. Conclusions ECM were useful marker for valuation of malignant degree in HCC. |
| |
| Keywords: | hepatocellular carcinoma extracellular matrix immunohistochemistry |
| 本文献已被 CNKI 维普 等数据库收录！ |
|
