6例人感染H7N9禽流感重症病例用药分析

目的:探讨重症人感染H7N9禽流感的治疗及合理用药。方法:对本院收治的6例重症人感染H7N9禽流感患者相关临床资料进行回顾性分析。结果:6例患者首发症状均表现出流感样症状,其中3例年龄在65岁以上并有基础疾病;6例患者治疗上以机械通气为主改善氧合,奥司他韦抗病毒,甲泼尼龙减轻炎症反应、抗生素抗感染、增强免疫、营养支持等综合措施;6例患者中4例治愈,1例死亡,1例病危。结论:早期有效的诊治、合理用药是降低H7N9高致病性禽流感病死率的关键。

Analysis of therapeutic drugs in severe patients with H7N9 avian influenza

OBJECTIVE To explore therapeutic method and rational medication for severe patients with H7N9 avian influenza.METHODS Clinical data of 6 patients with H7N9 avian influenza were analyzed retrospectively.RESULTS All 6 patients initially developed influenza-like symptoms. Three patients older than 65 years old had underlying diseases. All 6 patients were treated by mechanical ventilation, antiviral treatment with oseltamivir, methylprednisolone, antibiotics and nutritional support, immunity enhancement, etc. Four patients were discharged after cured. One patient died and one patient was critically ill.CONCLUSION Early and effective intervention and rational drug use are critical for reducing mortality.