云南白药联合泮托拉唑治疗急性上消化道出血的疗效观察

目的观察云南白药联合泮托拉唑治疗急性上消化道出血的临床疗效。方法将96例急性上消化道出血患者随机分为观察组、对照组各48例,对照组患者在对症治疗的基础上给予泮托拉唑静脉滴注,观察组在对照组基础上加用云南白药,两组均以3d为1个疗程,治疗1个疗程后观察并比较两组疗效。结果治疗1个疗程后,观察组显效率66.67%,总有效率91.67%;对照组显效率37.50%,总有效率72.92%。两组显效率、总有效率间差异均有统计学意义（均P〈0.05）。治疗1个疗程后,观察组止血时间、住院时间、输血量及总出血量均明显低于对照组,差异有统计学意义（均P〈0.05）。结论云南中药联合泮托拉唑治疗急性上消化道出血临床疗效显著,可明显缩短止血时间,减少输血量。

Clinical efficacy of Yunnan baiyao combined with pantoprazole in treatment of acute upper gastrointestinal hemorrhage

Objective To observe clinical effect of Yunnan Baiyao combined with pantoprazole in treatment of acute upper digestive tract hemorrhage.Methods 96 patients were randomly divided into the observation group and the control group with 48 cases in each group.Patients in the control group were gaven pantoprazole intravenous drip.In observation group,Yunnan Baiyao was orally given on base of the the control group.The two groups were treated for 3 days as one course of treatment,the therapeutic effects were observed after one course of treatment.Results The observation group showed an efficacy of 66.67%,the total effective rate was 91.67%,in the control group marked effective rate was 37.5%,the total efficacy was 72.92%.There were significant difference on the total efficacies between two groups（P0.05）.Bleeding time,volume of blood transfusion and bleeding volume,duration of hospitalizationin of the observation group were all less than that in control group（all P0.05）.Conclusion Yunnan Baiyao combined with Pantoprazole in treatment of acute upper gastrointestinal hemorrhage shows remarkable clinical curative effect with shortened bleeding time and decreased amount of blood transfusion.