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Antitumor and immunomodulating activities of the polysaccharide fractions fromArtemisia selengensis andArtemisia iwayomogi |
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| Authors: | Kyoung Ah Koo Jong Hwan Kwak Kang Ro Lee Ok Pyo Zee Eun Rhan Woo Ho Kun Park Hyun Joo Youn |
| Institution: | 1. Department of Microbiology, College of Natural Sciences, Inje University, 621-749, Kimhae, Kyungnam, Korea 2. Department of Pharmacy, College of Pharmacy, Sungkyunkwan University, 440-746, Suwon, Korea 3. Division of Chemistry, Korea Institute of Science and Technology, 136-791, Seoul, Korea |
| Abstract: | Effects of the polysaccharide fractions purified fromArtemisia selengensis andArtemisia iwayomogi on the immune system was studied. The polysaccharide fractions, respectively called ASP1 and AIP1, may interact with macrophages and lymphocytes in spleen, increasing the population of those cell typesin vivo andin vitro. Both ASP1 and AIP1 fractions also suppress transplanted tumor cell growth and augment antibody production. This study suggests that ASP1 and AIP1 fractions may have immunomodulating and antitumor activities. |
| Keywords: | Artemisia selengensis Artemisia iwayomogi Macrophage Lymphocyte Immunomodulating Antitumor |
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