鼻内镜术后中药鼻腔雾化吸入辅佐治疗慢性鼻-鼻窦炎的主客观评估

目的 评价慢性鼻-鼻窦炎(chronic rhinosinusitis， CRS)患者在鼻内镜术(endoscopic sinus surgery, ESS)后用中药进行鼻腔超声雾化吸入辅佐治疗的疗效。方法 63例CRS患者随机分为治疗组(33例)和对照组(30例)，ESS术后第3天行鼻腔超声雾化吸入。治疗组雾化用药为鼻窦炎口服液，每天早晚各1次，每次8mL，连续5d，后改为每周1次，连续3个月。对照组使用生理盐水鼻腔雾化吸入，方法相同。雾化前(术后第2天)、雾化5d和3个月后分别采用视觉模拟量表、Lund Kennedy评分系统、Lund Mackay评分法进行相关评估。结果 通过对主观症状、鼻内镜及鼻窦CT扫描进行检查评估，治疗组与对照组在雾化前后及组间比较差异均有统计学意义。结论 CRS患者ESS术后中药雾化吸入能明显提高手术疗效。

Subjective and objective assessment on chronic rhinosinusitis following adjuvant therapy of nasal inhalation withChinese medicine after endoscopic sinus surgery

Objective To evaluate the efficacy of nasal inhalation with Chinese medicine in chronic rhinosinusitis(CRS) after endoscopic sinus surgery (ESS). Methods 63 cases of CRS were randomly divided into the treatment group (33 cases) and the control group (30 cases),and all had nasal inhalation following endoscopic sinus surgery(ESS). Bidouyan-oral was used for the treatment group, twice a day, at 8mL, for five consecutive days, and then changed to once a week for 3 months. The control group used saline nasal inhalation, in the same way. Before inhalation， 5 days and 3 months later, the two groups were assessed in visual analogue scale, Lund-Kennedy score system and Lund-Mackay score system. Results On subjective symptoms, nasal endoscopy and sinus CT scan to check assessment, the difference between the treatment and control groups were significant. Before and after the spray the difference was also significant in each groups. Conclusion CRS patients after ESS for adjuvant use of traditional Chinese medicine treatment of inhalation, can significantly improve the surgical effect.