Pixel 2940nm激光对痤疮瘢痕治疗作用的定量评价

目的应用VISIA皮肤图像分析仪和SOFT5.5皮肤性质测试仪对Pixel 2940nm激光治疗痤疮瘢痕患者临床效果进行定量评价。方法随机选取45例痤疮瘢痕患者,应用Pixel 2940nm激光进行治疗,每月治疗一次,分别在治疗后1周,1月和3月用VISIA皮肤图像分析仪和SOFT5.5皮肤性质测试仪对患者皮肤性质进行定量分析和评价。结果治疗后3个月与治疗后1周相比,治疗后1周患者皮肤pH值下降(P<0.05),水分降低(P<0.05),油脂增高(P<0.05),pH值与油脂有明显负相关(P<0.01),弹性无明显变化(P>0.05);治疗前后比较变化最明显的是紫质(P<0.05),治疗后1周与治疗前相比,皱纹、纹理有明显差异(P<0.05),治疗后1月与治疗前相比紫外线色素斑减少(P<0.05),治疗后3月与治疗前相比毛孔和棕色斑减少(P<0.05),色素斑和红色区无明显改变(P>0.05)。结论 Pixel 2940nm激光对痤疮瘢痕患者皮肤性质改变主要在治疗后1周,表现为皮肤水分减少、油脂增高、紫质减少和毛孔肤质改善,临床应用VISIA皮肤图像分析仪和SOFT5.5皮肤性质测试仪对痤疮瘢痕患者治疗前后皮肤性质进行定量分析,可作为Pixel 2940nm激光治疗痤疮瘢痕的一个定量衡量标准,在诊断,指导治疗和疗效评估上具有一定意义。

Quantitation evaluation of Pixel 2940nm laser in treatment of atrophic acne scar

Objective Quantitation evaluation of Pixel 2940nm laser in the treatment of atrophic acne scar using VISIATM complexion analysis system and SOFT 5.5 skin property system.Methods Forty-five patients with atrophic acne acar were enrolled randomly in study during June to December 2010 in our laser center.Subjects received a total of 3 erbium laser treatments at one month intervals with the Wavelengths of 2940 nm,their skin properties were evaluated and analyzed by VISIATM complexion analysis system and SOFT 5.5 skin property system at 1 week,1 month and 3 months after the final treatment.Results All the patients completed the trial.Compared to 3 months after treament,skin pH was dropped(P<0.05),moisture was reduced(P<0.05),grease was heightened(P<0.05),pH and grease had obviously negative correlation(P<0.01) and elastic had no change(P>0.05) at 1 week after treatment.The most obvious changes before and after the treatment was purple mass(P<0.05).Compared to before treatment,wrinkles and texture numerical was heightened(P<0.05) at 1 week after treatment,UV pigment spot was reduced(P<0.05) at 1 month after treatment,march pores and brown spots was reduced(P<0.05) at 3 months after treatment.All patients’ pigment spot and red area did not changed significantly(P>0.05).Conclusion Pixel 2940nm laser affords a new treatment method for the treatment of atrophic acne scar and skin properties change is mainly appear at 1 week after treatment.The treatment effect showed mainly as skin grease,violet mass reduction and pore skin quality improvement.VISIATM complexion analysis system and SOFT 5.5 skin property system can be used as a quantized reference of curative effect for the Pixel 2940nm laser therapys.The two systems are useful for the diagnosis,guiding the therapy method and evaluating the therapeutic effect of atrophic acne scar.