Severe adenovirus pneumonia in immunocompetent adults: a case report and review of the literature |
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Authors: | F A Hakim I M Tleyjeh |
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Institution: | (1) Department of Internal Medicine, 4th Floor, Main Hospital, King Fahd Medical City, P.O. Box 59046, Riyadh, 11525, Saudi Arabia;(2) Division of Infectious Diseases, King Fahd Medical City, Riyadh, Saudi Arabia;(3) Division of Infectious Diseases, Mayo Clinic, College of Medicine, Rochester, MN, USA |
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Abstract: | Adenovirus is a frequent cause of mild self-limiting upper respiratory tract infection, gastroenteritis, and conjunctivitis
in infants and young children. Fatal infections (severe pneumonia progressing to respiratory failure, septic shock and/or
encephalitis) are rare among immunocompetent adults. We report a case of severe adenovirus pneumonia in a young immunocompetent
male who presented with sudden onset respiratory distress that progressed rapidly to respiratory failure and made a successful
recovery on supportive measures. Systematic review of the literature identified 14 cases of severe adenovirus pneumonia (defined
as respiratory failure requiring ventilatory support at any point during the course of illness) in otherwise healthy immunocompetent
adults both in epidemic and community settings. We describe the clinical characteristics, radiological features, and outcome
of identified cases. |
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Keywords: | |
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