Auxiliary Heterotopic Liver Transplantation With Portal Vein Arterialization for Fulminant Hepatic Failure |
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| Affiliation: | 1. Department of Endocrinology and Metabolism, Academic Medical Center, Amsterdam Lysosome Center ‘Sphinx’, Amsterdam, Netherlands;2. Department of Clinical Medicine, University of Bergen, Bergen, Norway;3. Department of Medicine, Haukeland University Hospital, Bergen, Norway;4. Unidad de Dialisis, IIS-Fundacion Jimenez Diaz/UAM, IRSIN, Madrid, Spain;5. Department of Pediatrics, Haukeland University Hospital, Bergen, Norway;6. Medical Genetics, Hospital São João, Faculty of Medicine of University of Porto, Porto, Portugal;7. Department of Nephrology, Academic Medical Center, Amsterdam, Netherlands;8. Manchester, UK;9. Department of Haematology, Royal Free London NHS Foundation Trust, & University College London, UK;10. Charles Dent Metabolic Unit, National Hospital for Neurology and Neurosurgery, London, UK;11. Department of Internal Medicine, Division of Nephrology, Ghent University Hospital, Ghent, Belgium;12. Department of Pathology, Academic Medical Center, Amsterdam, Netherlands;13. Department of Medicine, Division of Nephrology, University of Würzburg, Würzburg, Germany;14. Department of Nephrology, Dalhousie University, Halifax, Nova Scotia, Canada |
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| Abstract: | Auxiliary liver transplantation for patients with fulminant hepatic failure supports the patient's failing liver for a period of time until the native liver (NL) has recovered and immunosuppression can be withdrawn. Auxiliary heterotopic liver transplantation (AHLT) with portal vein arterialization (PVA) has several advantages over auxiliary orthotopic liver transplantation: NL resection is not required, and the hepatic hilum is left untouched; thus, the chances of liver regeneration are optimal. The successful application of emergency AHLT with PVA in a young patient who developed toxic fulminant hepatic failure caused by tuberculostatic drugs is described. Two and one-half months after the procedure, the NL had completely regenerated; the graft was removed, and immunosuppression was suspended. (Liver Transpl 2000;6:805-809.) |
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