Phytochemical screening and in vitro bioactivities of the extracts of aerial part of Boerhavia diffusa Linn. |
| |
Authors: | Apurba Sarker Apu Mahmuda Sultana Liza ATM Jamaluddin Md Amran Howlader Repon Kumer Saha Farhana Rizwan Nishat Nasrin |
| |
Institution: | Department of Pharmacy, East West University, Dhaka-1212, Bangladesh |
| |
Abstract: | ObjectiveTo investigate the bioactivities of crude n-hexane, ethyl acetate and methanol extracts of aerial part of Boerhavia diffusa Linn. (B. diffusa) and its phytochemical analysis.MethodsThe identification of phytoconstituents and assay of antioxidant, thrombolytic, cytotoxic, antimicrobial activities were conducted using specific standard in vitro procedures.ResultsThe results showed that the plant extracts were a rich source of phytoconstituents. Methanol extract showed higher antioxidant, thrombolytic activity and less cytotoxic activity than those of n-hexane and ethyl acetate extracts of B. diffusa. Among the bioactivities, antioxidant activity was the most notable compared to the positive control and thus could be a potential rich source of natural antioxidant. In case of antimicrobial screening, crude extracts of the plant showed remarkable antibacterial activity against tested microorganisms. All the extracts showed significant inhibitory activity against Candida albicuns, at a concentration of 1000 µg/disc.ConclusionsThe present findings suggest that, the plant widely available in Bangladesh, could be a prominent source of medicinally important natural compounds. |
| |
Keywords: | Boerhavia diffusa Antioxidant Cytotoxic Thrombolytic Antimicrobial DPPH NO |
本文献已被 ScienceDirect 等数据库收录! |
|