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Potential of surface acoustic wave biosensors for early sepsis diagnosis
Authors:Marie Csete  William D. Hunt
Affiliation:1. UCSD Anesthesiology, San Diego, CA, USA
2. AABB, Bethesda, MD, USA
3. Georgia Institute of Technology, Electrical and Computer Engineering, Atlanta, GA, USA
Abstract:Early diagnosis of sepsis is a difficult problem for intensivists and new biomarkers for early diagnosis have been difficult to come by. Here we discuss the potential of adapting a technology from the electronics industry, surface acoustic wave (SAW) sensors, for diagnosis of multiple markers of sepsis in real time, using non-invasive assays of exhaled breath condensate. The principles and advantages of the SAW technology are reviewed as well as a proposed plan for adapting this flexible technology to early sepsis detection.
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