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Cadaver fitting study of the DexAide right ventricular assist device
Authors:Ootaki Yoshio  Ootaki Chiyo  Kamohara Keiji  Akiyama Masatoshi  Cingoz Faruk  Kopcak Michael W  Dessoffy Raymond  Liu Jenny  Massiello Alex  Horvath David  Chen Ji-Feng  Zhou Qun  Benefit Stephen  Golding Leonard A R  Fukamachi Kiyotaka
Institution:Department of Biomedical Engineering, Lerner Research Institute, Cleveland Clinic, Cleveland, OH, USA.
Abstract:The DexAide right ventricular assist device (RVAD) has been developed to provide an implantable RVAD option to surgeons. The aim of this study was to determine the optimal cannula design and optimal implantation location of the DexAide RVAD in preparation for its clinical use. Separately, a HeartMate XVE left ventricular assist device (LVAD) and CorAide LVAD models were implanted into the preperitoneal and right thoracic space, and the anatomical fit of the DexAide RVAD was evaluated in five preserved human cadavers. The DexAide RVAD inflow cannula was inserted through the diaphragmatic surface of the right ventricle and the outflow was directed to the pulmonary artery. Right thoracic implantation of the DexAide RVAD provided an excellent fit with either the HeartMate or CorAide LVAD in all cadavers. The results of this study will guide improvements in the designs of cannulae and implantation of the DexAide RVAD in future clinical applications.
Keywords:Right ventricular assist device  Right ventricular failure  Circulatory support  Fitting study
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