不同方案保守治疗未破裂型异位妊娠126例临床分析

目的探讨米非司酮联合甲氨蝶呤用于治疗未破裂型异位妊娠的临床疗效。方法将126例异位妊娠患者随机分为两组，每组63例，观察组给予米非司酮联合甲氨蝶呤治疗，对照组单纯给予甲氨蝶呤治疗，记录两组患者血清HCG转阴时间和包块消失时间，比较两组患者1年后输卵管通畅率。结果治疗后的观察组血HCG转阴时间、包块消失时间优于对照组（P 〈 0.05）;观察组治愈成功率高于对照组（P〈0.05）；1年后，观察组输卵管通畅率优于对照组（P〈0.05）。结论米非司酮联合甲氨蝶呤可作为临床保守治疗异位妊娠的优良方案。

Clinical observation of mifepristone combined with methotrexate for un-ruptured ectopic pregnancy

Objective To Investigate the clinical efficacy of mifepristone combined with methotrexate for un-ruptured ectopic pregnancy. Methods One hundred and twenty-six cases of patients with un-ruptured ectopic pregnancy were randomly divided into the two groups. The observation group were treated with mifepristone combined with methotrexate, andthe control group were treated with only methotrexate. Recorded the time of Human Chorionic Gonadotropin （HCG） turning negative and the mass disappearing of the two groups patients, compared the rate of success and the tubal patency after1 year of the two groups. Results The observation group were better than the control group in the time of turning negativeand mass disappearing （P 〈 0.05）; the cure rate of the observation group was better than the control group （P 〈 0.05） ;Therate of the tubal patency of the observation group were better than that of the control group （P 〈 0.05）. ConclusionMifepristone combined with methotrexate can be used as a clinical conservative treatment of ectopic pregnancy excellentprogram.