冠心病患者血尿酸与总胆红素水平检测临床研究

目的探讨冠心病患者血尿酸与总胆红素水平检测的临床意义。方法选取我院收治的冠心病患者作为研究组，另选同期在我院进行健康体检的健康人群为对照组，分别对两组对象及研究组中不同血管病变组血清中血尿酸、总胆红素以及血脂相关指标的检测结果进行比较分析。结果与对照组健康人群相比，研究组冠心病患者SUA、TC、TG以及LDL—C水平均明显提高，而TBIL和HDL—C水平明显降低，差异均具有统计学意义（P〈0．05）。随着患者冠状动脉病变范围的扩大，血尿酸水平呈正相关，而总胆红素水平呈负相关。结论血尿酸与总胆红素与冠心病的发生和发展具有密切的关系，二者可以作为冠心病患者实验室诊断的参考指标，并能在一定程度上反应患者病情的严重性，为临床治疗提供一定的参考。

Clinical study of blood uric acid and total bilirubin level in patients with coronary heart disease

Objective To discuss the clinical significance of detection of serum uric acid and total bilirubin levels in patients with coronary heart disease. Methods Patients with coronary heart disease were known as the study group and healthy people were known as the control group in our hospital. The serum uric acid, bilirubin and blood lipid indexes were analyzed. Results Compared with the control group, the SUA, TC, TG and LDL-C levels were significantly in- creased in study group （P 〈 0.05）, but the TBIL and HDL-C levels were significantly decreased（P 〈 0.05）. Serum uric acid level was positively correlated to the degree of coronary artery stenosis and total bilirubin level was negatively correlated to the degree of coronary artery stenosis. Conclusion Serum uric acid and total bilirubin are closely related with the occurrence and development of coronary heart disease, which can be used as a reference index for laboratory diagnosis in patients with coronary heart disease. It can tell us the condition of patients in some degree and offer some reference for the clinical treatment.