男性体外受精-胚胎移植男性患者抑郁状况及影响因素分析

目的了解男性体外受精-胚胎移植(in vitro fertilization and embryo transfer,IVF-ET)男性患者的抑郁症状发生情况及其影响因素。方法 2013年2-9月在中南大学湘雅二医院不孕生殖中心便利抽取202例接受IVF-ET治疗的男性患者,于治疗周期的第1天进行问卷调查,包括一般情况问卷、抑郁自评量表、社会支持评定量表、Olson婚姻质量问卷(包括婚姻满意度、夫妻交流及性生活)。结果男性IVF-ET患者的抑郁发生率为49%;单因素分析显示,抑郁组男性IVF-ET患者的社会支持总分、客观支持及主观支持得分均低于无抑郁组,婚姻质量3个分量表总分和性生活得分低于无抑郁组,差异均有统计学意义(P0.01),且不同文化程度、住房面积、月收入、相关治疗费用、父母及自己对治疗的态度、舆论压力及是否有孩子者的抑郁发生率差异均有统计学意义(均P0.01);多因素Logistic回归分析显示,父母对治疗的态度、相关治疗费用及月收入是男性IVF-ET患者出现抑郁症状的重要影响因素(均P0.01)。结论接受IVF-ET治疗的男性患者有较高的抑郁发生率,且受多种因素影响,不孕生殖中心医务人员对该类人群应给予必要的心理支持和帮助。

Analysis of the Influencing Factors and Depression Status of Men Underwent In Vitro Fertiliza-tion and Embryo Transfer Treatment

Objective To explore the prevalence of depression of men who underwent in vitro fertilization and embryo transfer (IVF-ET)and its influencing factors.Methods Totally 202 men who visited the Infertility reproductive centers in the second xiangya hospital of central south university for IVF treat-ments were invited to join this study by randomize sampling method.All men completed Self-Designed Questionnaire,Self-Rating Depression Scale (SDS),Social Support Rating Scale (SSRS)and Olson Marital Inventory (marital satisfaction level,spouse communication and sexual activity)at first day of IVF treat-ment cycle.Results The overall prevalence of depression was 49% for men underwent IVF treatment.The single factor analysis result showed that the SSRS score,objective support and subjective support in men with depression were lower than norm,and the total score of three marital quality subscales and score in sexual activity were higher than men with no depression (P <0.01).There were statistical significance of the incidence rate of depression found in the men underwent IVF-ET with different education background, size of the house,monthly income,relevant treatment fee,parents and themselves attitude towards treat-ment,public opinion and whether has child (all P <0.01 ).The logistic regression analysis indicated that influential factors associated with depression were parents’attitude towards IVF treatment,infertility treatment expense and monthly income (all P <0.01 ).Conclusions The prevalence of depression of men underwent in vitro fertilization treatment is higher,and affected by multiple factors.The medical staffs in infertility reproductive center should provide patients with necessary psychological support.