理气药治疗肝癌作用及机理实验研究

目的：探讨理气药对肝癌的治疗作用及其机理，方法：理气药对3种肿瘤株荷瘤鼠的抑瘤实验，体外的过继抗癌免疫试验，淋巴细胞，NK细胞，吞噬细胞的功能测定；小鼠微循环观察，结果：理气药对H22肝癌瘤株有抑制作用（P＜0．05），能延长移植瘤的潜伏期，可通过脾细胞抑制肿瘤生长（P＜0．01），能增强吞噬细胞的活性，恢复荷瘤小鼠NK细胞的杀伤作用。能增强有丝分裂原诱导的T，B细胞功能，并可改善荷瘤小鼠的微循环，结论：理气药对肝癌转移瘤有明显的抑制作用。

To Study the Effect and Mechanism of the Medicine of Regulating Qi on Liver Cancer

Objective:To study the effect and mechanism of the medicine of regulating Qi(MRQ) on liver cancer.Method:The experiment of restraining cancer effect of MRQ on three kinds of cancer strains which are produced by the mouse with cancer;WINN experiment;The measuring of the functions determination of lymphocyte,NK cell,and megalophage;The observation of the micro-circulation of the mouse.Results:MRQ has the effect of restraining function to H 22 Liver cancer strain(P<0.05) and prolonging the latence of the transplantive cancer.The WINN experiment proved that MRQ can restrain the growth of cancer through spleen cell(P<0.01) and reinforce the activity of megalophage, recover the killer function of the NK cell of the mouse with cancer and strengthen the function of T cell,B cell tempted by mitoticgen;MRQ can also improve the micro-circulation of the mouse with cancer.Conclusion:MRQ can restrain prominently the transplantive cancer of liver cancer.