中西医结合治疗新型冠状病毒肺炎Meta分析

目的:评价中西医结合治疗新型冠状病毒肺炎(新冠肺炎)的疗效.方法:检索中西医结合治疗新冠肺炎的随机对照试验文献.进行文献筛选、资料提取及质量分析,采用RevMan 5.3软件分析数据.结果:共纳入10篇文献,1227例患者,中西医结合组658例,西医组569例.Meta分析结果显示中西医结合治疗与西医治疗比较,总体有效...

Meta-Analysis of COVID-19 Treated with Integrated Chinese and Western Medicine

Objective:To investigate the efficacy of integrated Chinese and western medicine in the treatment of COVID-19.Methods:Randomized controlled trials(RCTs)of COVID-19 treated with integrated Chinese and western medicine were searched.The retrieved literature was screened,and the data were extracted,and quality evaluation were carried out.RevMan 5.3 was applied for Meta-analysis.Results:Ten RCTs were included with 1227 patients,658 in the integrated Chinese and western medicine group and 569 in the western medicine group.The results showed that compared with western medicine alone,integrated Chinese and western medicine could improve the total effective rate(RR=1.26,95%CI[1.16,1.38],P<0.00001),the disappearance rate of clinical symptoms increased(RR=1.42,95%CI[1.19,1.69],P=0.0001),the progression rate of severe conditions decreased(RR=0.49,95%CI[0.34,0.72],P=0.0003),CT improvement rate increased(RR=1.26,95%CI[1.15,1.39],P<0.00001),white blood cell counts decreased(MD=0.38,95%CI[0.31,0.44],P<0.00001).Conclusion:In the treatment of COVID-19,integrated Chinese and western medicine could significantly improve the total effective rate,reduce the clinical symptoms and progression rate of server conditions.