丹参多酚酸注射液联合阿托伐他汀钙片治疗脑梗死疗效及对患者血液流变学影响

目的:探讨丹参多酚酸注射液联合阿托伐他汀钙片治疗脑梗死疗效及对患者血液流变学的影响.方法:选取脑梗死患者126例,通过摸球法将患者随机分为对照组(n=63)、观察组(n=63).两组患者均接受脑梗死常规治疗,对照组给予阿托他汀钙片治疗,观察组在对照组基础上联合使用丹参多酚酸注射液治疗.比较两组患者疗效、血液流变学指标、...

Effect of salvia miltiorrhiza polyphenolic acid injection combined with atorvastatin calcium tablets on cerebral infarction and its effect on hemorheology

Objective:To explore effect of salvia miltiorrhiza polyphenolic acid injection combined with atorvastatin calcium tablets on patients with cerebral infarction and on hemorheology.Methods:126 patients with cerebral infarction were randomly divided into control group(n=63)and observation group(n=63)by ball-touching method.Both groups received conventional treatment for cerebral infarction,the control group was given atorstatin calcium tablets for treatment,and the observation group treated with salvia miltiorrhiza polyphenolic acid injection on the basis of the treatment of the control group.The efficacy,hemorheology index,blood lipid index,NIHSS score,ADL score and adverse reactions were compared between the two groups.Results:After treatment,the levels of TG,HDL-C and TC in the observation group were lower than those in the control group,and the HDL-C level was higher than that in the control group,difference statistically significant(all P<0.05).The plasma specific viscosity,whole blood high shear viscosity,whole blood low shear viscosity,fibrinogen and hematocrit of the observation group were lower than those in the control group,difference statistically significant(all P<0.05).The NIHSS score of the observation group was lower than that in the control group and ADL score higher than that in the control group,difference statistically significant(all P<0.05).The total effective rate of 96.83%in the observation group was significantly higher than 84.13%in the control group,difference statistically significant(all P<0.05).There was no significant difference in adverse reactions between the two groups(P>0.05).Conclusion:Salvia miltiorrhiza acid injection combined with atorvastatin calcium tablet has good efficacy in the treatment of cerebral infarction,which can effectively improve blood lipid and hemodynamic indexes,improve the neurological function and quality of life of patients,better safety.