女性不孕与解脲支原体和沙眼衣原体感染的关系

目的:了解泸州地区女性不孕患者泌尿生殖道解脲支原体(UU)、沙眼衣原体(CT)感染现状,探讨女性感染UU、CT后与不孕的关系。方法:采用荧光定量聚合酶链反应(FQ-PCR)技术对238例女性不孕者(不孕组)和208例正常生育者(对照组)的宫颈分泌物进行UU、CT检测。结果:不孕组UU阳性率为36.97%(88/238),CT阳性率为30.25%(72/238),UU+CT阳性率为14.29%(34/238);对照组UU阳性率为13.46%(28/208),CT阳性率为10.58%(22/208),UU+CT阳性率为4.81%(10/208)。不孕组UU、CT和UU+CT的阳性检出率均明显高于对照组(P<0.01)。结论:生育期女性生殖道感染UU、CT是导致不孕的重要因素之一,对不孕妇女常规进行UU、CT检测并及时治疗非常必要。

The relationship between women infertile and Ureaplasma Urealyticum and Chlamydia Trachomatis

Objective:To study the infection of ureaplasma urealyticum (UU) and Chlamydia trachomatis (CT) in infertile women in Luzhou area and to explore the association of UU、CT infection with infertility.Methods:Fluorescent quantitative polymerase chain reaction (FQ-PCR) was used to detect quantitatively UU DNA and CT DNA in reproductive tract secretion of 238 infertile women and 208 normal women.Results:In infertility group: UU positive rate was 88/238(36.97%),CT positive rate was 72/238(30.25%),UU+CT positive rate was 34/238 (14.29%); In normal group: UU positive rate was 28/208 (13.46%),CT positive rate was 22/208(10.58%),UU+CT positive rate was 10/208(4.81%). There were significant differences in positive rate of UU,CT and UU+CT between the infertile women and the normal women group (P<0.01).Conclusion:Infection with UU and CT in women's reproductive tract is one of the factors causing infertility. It is necessary for the infertile women to receive the routine examine and treatment in time.