参附注射液对体外循环患者cTnI水平的影响

目的：探讨参附注射液（SFI）对体外循环（CPB）心脏手术患者心肌肌钙蛋白Ⅰ（cTnI）水平的影响。方法：选择临床心内直视手术患者60例,随机分为对照组和参附预处理组（SFI组）组各30例,SFI组于CPB前予参附注射液在转机前以微泵注射,对照组按常规手术。分别记录术前、术中60min、120min、术后6h两组患者cTnI水平。结果：SFI组术中60min、120min、术后6h各时点cTnI均低于对照组,两组比较有显著性差异（P〈0.05）。结论：参附注射液对CPB患者心肌细胞再灌注有保护作用,值得临床推广应用。

Effect of Shengfu injection on cardiac troponin I of patients with CPB

Objective: To explore the effect of Shenfu injection on cardiac troponin I of patients with CPB.Methods: Sixty patients subjected to intracardiac operation under direct vision were randomly into control group(n=30) and Shenfu group(n=30).Shenfu injection was given to patients with minipump before CPB in Shenfu group and patients were operated conventionally.The level of cTnI was recorded before CPB,60min.and 120min.in CPB and 6 h after CPB.Results: All the level of cTnI at the time mentioned above was lower in Shenfu group than that in the control group and there was significant difference in the comparison(P<0.05).Conclusion: Shenfu injection has the protection to some extent from myocardial injury during CPB.