| 急性心肌梗死患者经皮冠状动脉介入治疗前后脑利钠肽水平的变化及其意义 |
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| 引用本文： | 涂颉洪,戴月.急性心肌梗死患者经皮冠状动脉介入治疗前后脑利钠肽水平的变化及其意义[J].国外医学：内科学分册,2008,35(12). |
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| 作者姓名： | 涂颉洪 戴月 |
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| 作者单位： | [1]南昌市第一医院心血管内科,江西南昌330008 [2]江西护理职业技术学院,江西南昌330201 |
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| 摘 要： | 目的 研究急性心肌梗死(AMI)患者接受经皮冠状动脉介入(PCI)治疗前后血浆脑利钠肽(BNP)水平变化及其与心功能、心室重构的关系.方法 入选2005年9月至2008年3月,发病后12 h内接受急诊PCI治疗的ST段抬高急性心肌梗死患者102例,直接PCI前及直接PCI后第7天采用酶联免疫法测定患者血浆BNP水平,并按治疗后第7天血浆BNP水平将患者分为3组:A组低于100 pg/ml,B组100～400 pg/ml,C组高于400 pg/ml,PCI治疗后6个月对患者进行超声心动图检查.结果 PCI治疗后BNP水平较治疗前明显下降;3组患者PCI治疗后6个月的超声心动图比较,患者左室射血分数、左室舒张末期容积、左室收缩末期容积C组与A、B组差异有统计学意义(P＜0.05),B组与A组比较差异无统计学意义(P＞0.05).结论 AMI患者直接PCI后BNP水平有显著下降趋势,且BNP水平可能可以作为患者心功能及心室重构的预测因子.
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| 关 键 词： | 急性心肌梗死 经皮冠状动脉介入治疗 脑利钠肽 心功能 心室重构 |
The changes of brain natriuretic peptide level and its significance in patients with acute myocardial infarction before and after primary percutaneous coronary intervention |
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| TU Jie-hong,DAI Yue.The changes of brain natriuretic peptide level and its significance in patients with acute myocardial infarction before and after primary percutaneous coronary intervention[J].Foreign Medical Sciences(Section of Internal Medicine),2008,35(12). |
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| Authors: | TU Jie-hong DAI Yue |
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| Institution: | TU Jie-hong,DAI Yue.Department of Cardiology,The First Hospital of Nanchang,Nanchang 330008,China |
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| Abstract: | Objective To investigate the changes of brain natriuretic peptide(BNP) of patients with acute myocardial infarction before and after percutaneous coronary intervention(PCI) and its relationship with cardiac function and ventricular remodeling.Methods One hundred and two patients with ST-segment elevation myocardial infarction were successfully reperfused by primary PCI within 12 hours after onset.BNP plasma level of the patients was measured with enzyme-linked immunoassay before and 7 days after PCI.Accordi... |
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| Keywords: | Acute myocardial infarction Percutaneous coronary intervention Natriuretic peptide Cardiac function Ventricular remodeling |
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