自体前板层角巩膜缘移植治疗角膜重度碱烧伤

目的:探讨自体前板层角巩膜缘移植治疗角膜周边部小面积重度碱烧伤的临床疗效及安全性。方法:对39例39眼角膜周边部小面积重度碱烧伤患者,行局部清创,切除病灶处前板层角膜及邻近板层巩膜、部分结膜,取健眼相对应处的前板层角巩膜及结膜移植,术后观察患者主观症状(疼痛、畏光、流泪)、视力、角膜上皮修复时间及复发情况,健眼的视力、伤口恢复及并发症。结果:术后随访2～12mo,所有患者角膜上皮全部愈合,患者主观症状恢复快,均未发生视力下降,无1例复发;健眼角巩膜缘伤口愈合良好,未出现并发症。结论:自体前板层角巩膜缘移植治疗角膜周边小面积重度碱烧伤,手术操作简单,可有效缩短角膜碱烧伤的愈合时间,促进角膜上皮修复,健眼(供体眼)恢复良好,无严重并发症发生。

Self front plate layer sclera edge transplantation in treatment of corneal severe alkali burn

AIM: To study the clinical curative effect and securityof autologous front plate layer sclera edge transplantation in treatment of corneal peripheral small area severe alkali burn.

METHODS:Totally 39 cases(39 eyes)with corneal peripheral small area severe alkali burn were included, they underwent local debridement, excision of infection at the front plate layer of corneal and adjacent lamellar sclera, also part of the conjunctiva, the front plate layer sclera and conjunctival in the corresponding health eye was taken and transplanted. Patients' postoperative subjective symptoms(pain, photophobia, and tears), vision, corneal epithelium time to repair and recurrence, the healthy eye eyesight, healing and sequel were observed.

RESULTS:After postoperative follow-up of 2-12 months, all patients' corneal epithelium healed, patients subjective symptoms rapidly recovered, no vision loss occurred, no relapse. Health canthus sclera edge wound healing was good, without sequela.

CONCLUSION:Autologous front plate sclera transplantation in the treatment of corneal peripheral small area severe alkali burn, the operation is simple, which can effectively shorten the corneal alkali burn healing time, promote corneal epithelium repair, health eyes(donor eyes)good recovery, without sequelae.