| 表皮生长因子促进创面愈合的方法学研究 |
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| 引用本文： | 谷廷敏,王玉舟,孙志刚,刘建春,杨建民,牛星焘,陈东明. 表皮生长因子促进创面愈合的方法学研究[J]. 现代中西医结合杂志, 2001, 10(5): 389-391 |
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| 作者姓名： | 谷廷敏 王玉舟 孙志刚 刘建春 杨建民 牛星焘 陈东明 |
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| 作者单位： | 1. 白求恩国际和平医院烧伤整形科,河北省石家庄市,050082
2. 北京大学医学部第三附属医院成形科,100083 |
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| 摘 要： | 目的 :探讨不同 EGF用药方法对创面愈合的影响 ,进一步理解创面愈合的机制。方法 :以大鼠为模型 ,于大鼠后背取中厚皮创面 4个 ,分 EGF早期用药组、EGF晚期用药组、EGF持续用药组和对照组 ,观察 EGF用药方法对创面愈合的影响。结果 :应用 EGF后创面愈合速度加快 ,持续用药方法优于早期或晚期用药方法。结论 :通过组织学和超微结构的观察 ,揭示了创面修复的机理和 EGF的作用。
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| 关 键 词： | 表皮生长因子 创面愈合 用药方法 |
Study on the application method of EGF to promote wound healing |
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| Gu Tingmin,Niu Xingtao,Wang Yuzhou,et al The Center of Plastic Surgery,the Third Affiliated Hospital of Beijing Medical University,Beijing. Study on the application method of EGF to promote wound healing[J]. Modern Journal of Integrated Chinese Traditional and Western Medicine, 2001, 10(5): 389-391 |
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| Authors: | Gu Tingmin Niu Xingtao Wang Yuzhou et al The Center of Plastic Surgery the Third Affiliated Hospital of Beijing Medical University Beijing |
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| Affiliation: | Gu Tingmin,Niu Xingtao,Wang Yuzhou,et al The Center of Plastic Surgery,the Third Affiliated Hospital of Beijing Medical University,Beijing 100083 |
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| Abstract: | Objective: It is to explore the effect of different application method of EGF on wound healing. Methods: Four partial-thickness skin wounds were made on the dorsum of rat and each of the wound was given different application method of EGF: early application method, late application method, persistant application method and control method. Results: EGF can promote the speed of wound healing, persistant application method is better than the early application or the late application method. Conclusion: The mechanism is discussed. |
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| Keywords: | epidermal growth factor wound healing application method |
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