长期辐射对男性放射工作人员外周血T、B、NK淋巴细胞的影响

目的]探讨长期辐射对男性放射人员T、B、NK淋巴细胞亚群水平的影响。方法]检测32名男性放射工作人员T、B、NK细胞中各亚群在淋巴细胞中的百分率，按受照辐射总剂量进行分组比较。结果]CD3^＋CD8^＋T在≤20mSv和〉20mSv组间的百分比分别为（24．91±7．21）％和（18．68±6．99）％，差异具有统计学意义（t：2．430，P〈0．05），CD8^＋CD45RO^＋T在≤20mSv和〉20mSv组间的百分比分别为（6．54±2．65）％和（4．15±1．93）％，差异具有统计学意义（t=2．780，P〈0．01）。结论]长期电离辐射能引起CD3^＋CD8^＋T和CD8^＋CD45RO^＋T的降低，应加强监控。

Effects of Long-term Ionizing Radiation on T, B and NK Lymphocyte Subsets in Peripheral Blood of Male Roentgenogramphy Workers

Objective ] To investigate the effects of long-term ionizing radiation on T, B and NK lymphocyte subsets in peripheral blood of male roentgenography workers. Methods ] The T, B and NK lymphocyte subsets in the peripheral blood lymphocyte of 32 male roentgenography workers were examined and compared among stratified groups with gradient radiation dose. Results ] There were significant difference （t = 2.430, P〈 0.05） between the percents of CD3^＋CD8^＋T cells in lymphocyte of ≤ 20mSv group （24.91 ± 7.21）% ]versus 〉20mSv group （18.68 ± 6.99）% ]. The percents of CD8^＋CD45RO^＋T cells in lymphocyte between ≤ 20mSv group （6.54± 2.65）% ]versus 〉20mSv group （4.15 ± 1.93）% ] were significantly different also （t= 2.780, P〈0.01）. Conclusion ] Reduction of CD3^＋CD8^＋T and CD8^＋CD45RO^＋T subsets of lymphocyte may be resulted in long-term ionizing radiation in male roentgenography workers. Attention in monitoring on these changes should be enforced.