自拟理肺化瘀方治疗支气管哮喘的效果观察

目的：观察自拟“理肺化瘀”方治疗支气管哮喘的疗效。方法102例支气管哮喘患者按照数字表法随机分为观察组和对照组，各51例。对照组采用常规治疗，观察组在常规治疗的基础上加用自拟“理肺化瘀”方治疗。两组共治疗8周。观察两组疗效和测定两组患者的肺功能和血气分析，包括第1秒用力呼气容积（ FEV1）、用力吸气肺活量（ FVC）、最大呼气流量（ PEF）、pH 值、氧分压（ PaO2）和二氧化碳分压（PaCO2）。结果观察组总有效率为98．0％，明显高于对照组的90．2％（χ2＝5．78，P＜0．05）；两组治疗后FEV1、FVC和PEF均明显提高（t＝5．325、4．821、2．761，均P＜0．05），且观察组提高更明显（t＝2．068、2．771、3．013，均P＜0．05）；两组治疗后PaO2均明显升高，且观察组升高更明显（t＝2．925，P＜0．05），两组治疗后PaCO2均明显降低，且观察组降低更明显（t＝3．063，P＜0．05）。结论自拟“理肺化瘀”方治疗支气管哮喘的疗效明确，且可以明显改善患者的肺功能和血气指标。

Effects of selfmade Lifeihuayu decotion in the treatment of patients with bronchial asthma

Objective To observe the effects of selfmade Lifeihuayu decotion in the treatment of patients with bronchial asthma.Methods 102 patients with bronchial asthma were randomly divided into the observation group and the control group,each group had 51 cases.The patients in the control group were treated with the conven-tional treatment,while the patients in the observation group were treated with the conventional treatment plus selfmade Lifeihuayu decotion.They were treated for 8 weeks.The patients of the two groups were determined with lung function and blood gas analysis, including forced expiratory volume in one second （ FEV1 ） , forced inspiratory vital capacity （ FVC） ,peak expiratory flow（ PEF） ,pH value,the partial pressure of oxygen（ PaO2 ） and carbon dioxide partial pres-sure（PaCO2）.Results The total effective rate were 98.0% in the observation group and 90.2% in the control group,the total efficiency of the observation group was significantly higher（χ2 =5.78,P〈0.05）.After treatment,the FEV1,FVC and PEF of the patient＇s in the two groups were significantly increased（t=5.325,4.821,2.761,all P〈0.05）,and compared with the control group,the FEV1,FVC and PEF of patients in the observation group improved more significantly（t=2.068,2.771,3.013,all P〈0.05）.After treatment,the PaO2 of the patient＇s in the two groups were significantly higher,which more obviously increased in the observation group than those in the control group（ t=2.925,P〈0.05）.After treatment,the PaCO2 of the patient＇s in the two groups were significantly decreased,PaCO2 in the observation group significantly decreased more than that in the control group（t=3.063,P〈0.05）.Conclusion Selfmade Lifeihuayu decotion in the treatment of patients with bronchial asthma has curative effect,and can signifi-cantly improve lung function and blood gas analysis of patients.