振幅整合脑电图在新生儿缺氧缺血性脑病早期诊断中的意义

目的 探讨振幅整合脑电图(aEEG)在新生儿缺氧缺血性脑病(HIE)早期诊断中的意义.方法 选择HIE足月儿42例为研究对象,临床分为轻、中、重三度.选择同期健康足月儿10例为健康对照组.并对所有观察对象进行脑电图描记及振幅整合,按aEEG结果将其分为正常aEEG、轻度异常aEEG、重度异常aEEG 3种.采用SPSS 13.0软件进行统计学分析.结果 42例HIE患儿中,aEEG正常者18例,其中16例为轻度HIE( 88.9％),2例为中度HIE( 11.1％)；aEEG轻度异常者15例,其中3例为轻度HIE (20.0％),9例为中度HIE( 60.0％),3例为重度HIE( 20.0％)；aEEG重度异常者9例,其中2例为中度HIE (22.2％),7例为重度HIE( 77.8％).而10例健康对照组aEEG均为正常.aEEG监测结果与HIE临床分度密切相关(K=0.633,P＜0.001).结论 aEEG可作为一种简化的脑功能评价方法,用于HIE新生儿的早期诊断及病情预测.

Significance of Amplitude Integrated Electroencephalography in Early Diagnosis of Hypoxic-Ischemic Ence-phalopathy in Newborn Infants

Objective To evaluate the significance of the amplitude integrated electroencephalography(aEEG) in early diagnosis of neonates with hypoxic-ischemic encephalopathy(HIE). Methods Forty-two term infants with HIE and 10 healthy term infants were stu-died by aEEG.The HIE was clinically classified into 3 grades(mild,moderate and severe),and the results of aEEG were categorized into three groups(normal aEEG,mildly abnormal aEEG,severely abnormal aEEG).SPSS 13.0 software was used to analyze the data. Results Among...