| 血脂康对急性冠脉综合征患者内皮功能的影响 |
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| 引用本文： | 王弋,陈雯,吴锦鸿,许国根. 血脂康对急性冠脉综合征患者内皮功能的影响[J]. 中国药业, 2007, 16(12): 30-31 |
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| 作者姓名： | 王弋 陈雯 吴锦鸿 许国根 |
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| 作者单位： | 浙江省杭州市第一人民医院急诊科,浙江,杭州,310003 |
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| 摘 要： | 目的观察血脂康对急性冠脉综合征患者血清一氧化氮（NO）及一氧化氮合酶（NOS）的影响。方法随机选择急性冠脉综合征病患者67例．将其随机分为血脂康治疗组35例，阿托伐他汀组32例，并对两组患者治疗前后血清NO及NOS含量水平进行对比分析。结果血脂康和阿托伐他汀均可升高急性冠脉综合征患者血清NO及NOS水平，其作用无明显差异（P〉0．05）。结论血脂康可抑制脂质过氧化反应．保护血管内皮功能，对急性冠脉综合征的防治具有重要意义。
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| 关 键 词： | 冠心病 一氧化氮 一氧化氮合酶 血脂康 |
| 文章编号： | 1006-4931（2007）12-0030-02 |
| 修稿时间： | 2007-02-08 |
Effects of Xuezhikang on Nitric Oxide and Nitric Oxide Synthase in Acute Coronary Syndrome |
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| Affiliation: | (Department of Emergency,First People's Hospital of Hangzhou,Hangzhou,Zhejiang,China 310003) |
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| Abstract: | Objective To investigate the effects of Xuezhikang on serum nitric oxide(NO)and nitric oxide synthase(NOS)in acute coronary syndrome(ACS).Methods 67 cases of ACS were divided into two groups,xuezhikang group 35 cases and atorvastatin group 32 cases.The level of serum NO and NOS before and after therapy were analyzed comparatively.Results Xuezhikang and atorvastatin could increase the level of NO and NOS in ACS, the effect was not obviously different.Conclusion Xuezhikang can restrain lipid oxidation and preserve vascular endothelial function by regulating lipid therapy,and has the important significance for prevention and cure of ACS. |
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| Keywords: | coronary heart disease nitric oxide nitric oxide synthase Xuezhikang |
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