肺癌早期诊断的临床进展

肺癌是发病率及病死率增长最为迅速的恶性肿瘤，已成为威胁人类健康和癌症死亡主要病因之一。肺癌5年生存率13％～15％，早期诊断率仅15％。提高肺癌的早期诊断是改善肺癌5年生存率的关键。整合影像学方法和微创检查技术，同时开展痰细胞学检查、血清肿瘤标记物测定对提高肺癌的早期诊断具有临床意义。本文回顾影像学诊断方法、痰细胞学检查、微创介入诊断技术临床应用，以及近年来国外开展的肺癌诊断技术的临床进展。

The Progress on Clinical Early Diagnostic Methods of Lung Cancer

Among malignant tumors, the incidence and mortality rates of lung cancer have increased rapidly and has become a major threat to the health of the people. The five-year survival rate of lung cancer is 13% - 15%. Early diagnosis amounted to just 15%. Elevating the early diagnosis rate is imperative to improve the five-year survival rate. From the clinical point of view, the employment of integrated imaging technique, minor traumatic examination method, the use of sputum cell examination and determination of serum tumor markers all help to elevate the early diagnosis rate. This report recapitulates the imaging diagnostic method, sputum cytology examination, determination of serum tumor markers, the use of minor traumatic intervening clinical methods and also the recent advances in lung cancer diagnosis as well as clinical diagnostic methods of foreign countries.