不同发病部位原发性胃癌患者临床病理特征比较

目的 比较分析不同发病部位原发性胃癌患者的临床病理特征.方法 手术成功且术后病理及随访资料齐全的胃癌病例318例,其中胃上部癌82例,胃中部癌90例,胃下部癌146例.结果 3组患者性别和年龄比较有显著性差异(P<0.05),而BMI比较无显著性差异(P>0.05).3组患者手术根治情况、病灶大小、分化程度、浸润深度和病理学分期存在显著性差异(P<0.05或P<0.01),而淋巴结转移、生长方式和组织学分型方面比较无显著性差异(P>0.05).胃上部癌患者5年生存率显著低于胃中部癌和胃下部癌患者(P<0.05).结论 不同发病部位原发性胃癌患者临床病理特征存在差异,认识不同部位胃癌的临床病理特征,为患者提供个体化的治疗方案,对改善患者预后具有重要的指导意义.

Clinicopathologic Features of Gastric Carcinoma in Different Position

Objective To investigate the clinicopathologic features of gastric carcinoma in different position .Methods 318 cases of patients with gastric carcinoma were successfully treated ,proximal,middle and lower gastric carcinoma patients were 82 cases,90 cases and 146 cases,respectively.Results There was significant difference in gender and age among proximal ,mid-dle and lower gastric carcinoma patients (P<0.05),while there was no significant difference in BMI (P>0.05).There was sig-nificant difference in operation eradication ,tumor size,differentiation degree ,invasion depth and histopathologic stage among prox-imal,middle and lower gastric carcinoma patients (P<0.05 or P<0.01),while no significant difference was found for lymphatic metastasis,growth way and tissue type (P>0.05).Conclusion Proximal,middle and lower gastric carcinoma patients showed different clinicopathologic features and biological behaviors .Knowing the difference clinicopathologic feature and biological behav-ior of proximal ,middle and lower gastric carcinoma can provide specific treatment for patients ,which is good for improving progno-sis.