甲状腺癌的临床诊治特点及治疗效果比较分析

目的 探讨甲状腺癌的临床诊治特点及治疗效果.方法 收集甲状腺癌的病患420例,对其按时间段进行分组,7年为1个时间段,研究甲状腺癌的临床特点变化,并分析影响其治疗效果的因素.结果 2001-2007年与2008-2014年两个时间段甲状腺癌患者的年龄分布在相对应的年龄上发病率没有明显差异,无统计学意义(P>0.05),但在每个时间段中,甲状腺癌的发病率集中在41~50岁上,差异具有统计学意义(P<0.05).2001-2007年和2008-2014年2个时间段的甲状腺癌的发病率在性别上均为女性多于男性,差异具统计学意义(P<0.05).2001-2007年和2008-2014年2个时间段的甲状腺癌在发病年龄、病灶的单发与多发以及肿瘤直径上差异不具统计学意义(P>0.05).但是2组患者无论从性别、年龄、病灶的多寡还是肿瘤直径以及淋巴结清扫阳性率上均具有统计学差异(P<0.05).甲状腺癌全切手术组和次全切手术组对比发现,全切手术组在术中出血量、手术时间以及术后低钙血症发生率上与次全切手术组存在差异,具有统计学意义(P<0.05).甲状腺癌全切手术和次全切手术2种手术方式在甲状旁腺损伤(10.00%/6.00%)、喉返神经损伤(10.00%/8.00%)以及喉上神经损伤(5.00%/7.00%)的发生率上差异不具有统计学意义(P>0.05).结论 甲状腺癌的发生率近年来呈上升趋势,且存在多种危险因素影响其发生发展,不同手术方式影响到甲状腺癌预后,应根据具体情况选择合理的手术方式.

Clinical Characteristics and Efficacy of Thyroid Cancer

Objective To investigate the clinical characteristics and efficacy of thyroid cancer .Methods 420 patients with thyroid cancer were divided into 2 groups according to time ,every 7 year was a period .Changes of clinical characteristics of thyroid carcinoma were detected ,and risk factors of efficacy of thyroid cancer were analyzed .Results The age distribution of pa-tients with thyroid cancer between 2001-2007 and 2008-2014 period had no significant difference (P>0.05),but in each time period,the incidence of thyroid carcinoma was concentrated in the 41~50 years old,the difference was statistically significant ( P<0.05).The incidence of thyroid cancer patients in 2001-2014 years had more females than males ,there was statistically sig-nificant difference(P<0.05).There had no difference in age,unifocal or multifocaland tumor diameter of patients of thyroid cancer between 2001-2007 and 2008-2014(P>0.05).There had significant difference in gender ,age,number of lesions and diameter of the tumor and the lymph node dissection positive rate between the 2 groups(P<0.05).Between the thyroid cancer resection group and subtotal resection group ,there were statistical differences in intraoperative bleeding ,operation time and post-operative hypocalcemia incidence (P<0.05).Thyroid carcinoma total resection and subtotal surgery in the incidence of parathy -roid injury(100.00%/6.00%),injury of recurrent laryngeal nerve (10.00%/8.00%) and injury of superior laryngeal nerve (5.00%/7.00%) had no significant difference (P>0.05).Conclusion The incidence of thyroid cancer has increased in re-cent years ,and there are many risk factors affecting the occurrence and development of thyroid cancer .Different operation methods have different influence on the results of the thyroid cancer ,surgical method should be selected according to circumstances .