参麦注射液联合TP化疗方案对乳腺癌术后患者的疗效观察及生存质量的影响 |
| |
引用本文: | 魏荣富,金茂勇.参麦注射液联合TP化疗方案对乳腺癌术后患者的疗效观察及生存质量的影响[J].实用癌症杂志,2016(7):1088-1090. |
| |
作者姓名: | 魏荣富 金茂勇 |
| |
作者单位: | 211300,江苏省南京市高淳人民医院 |
| |
摘 要: | 目的探讨参麦注射液联合TP化疗方案对乳腺癌术后患者的疗效及生存质量的影响。方法将80例患者按照随机数字表法随机分为2组,分别为对照组(n=39)和观察组(n=41)。对照组采用TP化疗方案治疗,观察组在对照组基础上结合参麦注射液治疗。对比分析2组治疗前后Karnofsky评分变化、近期疗效、T淋巴细胞亚群变化。结果2组Karnofsky评分治疗后较治疗前显著增加(P〈0.05);观察组Karnofsky评分治疗后显著高于对照组(P〈0.05);观察组有效率(63.41%)显著高于对照组(35.90%)(P〈0.05)。观察组CD3^+、CD4^+、CD4^+/CD8^+治疗后较治疗前明显增加,CD8^+较治疗前明显减少,且具有统计学差异(P〈0.05);观察组CD3^+、CD4^+、CD4^+/CD8^+治疗后显著高于对照组,而CD8^+治疗后显著低于对照组(P〈0.05)。结论参麦注射液联合TP化疗方案对乳腺癌术后患者近期疗效显著,可明显提高患者生存质量。
|
关 键 词: | 参麦注射液 TP化疗方案 乳腺癌 近期疗效 免疫功能 |
Influence of Shenmai Injection Combined with TP Chemotherapy on Efficacy and Quality of Life of Breast Cancer Patients after Surgery |
| |
Abstract: | Objective To study the influence of shenmai injection combined with TP chemotherapy on efficacy and qual -ity of life of breast cancer patients after surgery .Methods 80 patients according to the random number table ,were randomly di-vided into the control group(n=39) and the observation group(n=41).The control group received TP chemotherapy ,the obser-vation group received shenmai injection on the basis of the control group .Comparison of Karnofsky score changes , short-term effect,T lymphocyte subsets of the 2 groups before and after treatment were analyzed .Results Karnofsky score of the 2 groups after treatment significantly increased (P<0.05);Karnofsky score of the observation group after treatment was significantly higher (P<0.05);observation group was(63.41%) was significantly higher than that of the control group (35.90%)(P<0.05). CD3 +,CD4+,CD4 +/CD8 +of the observation group after treatment significantly increased ,CD8 +after treatment significantly re-duced,and there had significant difference (P<0.05);CD3 +,CD4 +,CD4 +/CD8 +of the observation group after treatment was significantly higher than those of the control group ,but CD8 +of the observation group after treatment was significantly lower than that of the control group(P<0.05).There Karnofsky scores after treatment than before treatment significantly increased (P<0.05);Karnofsky score was observed after treatment group was significantly lower than the control group ( P<0.05);observation group efficiency(63.41%) was significantly higher(35.90%)(P<0.05);observation group CD3+,CD4 +,CD4 +/CD8 +after treatment significantly increased than before treatment , CD8 + significantly reduced compared with that before treatment ( P <0.05);observation group CD3 +,CD4 +,CD4 +/CD8 +after treatment was significantly higher ,while CD8 +after treatment was significantly lower than the control group (P<0.05).Conclusion Shenmai injection combined with TP chemotherapy for breast cancer has significant recent efficacy ,it can significantly improve the quality of life of patients . |
| |
Keywords: | SMI liquid TP chemotherapy Breast cancer Curative effect Immune function |
本文献已被 维普 万方数据 等数据库收录! |
|