年龄相关性黄斑变性脉络膜新生血管治疗的几个重要问题

近年来,在治疗年龄相关性黄斑变性导致的脉络膜新生血管方面取得了很大进展.但是,要取得良好的治疗效果,有几个问题必须明确.即典型性脉络膜新生血管还是隐匿性脉络膜新生血管,是否是息肉状脉络膜血管病变或是视网膜血管瘤样增生,治疗时选择光动力疗法还是抗血管内皮细胞生长因子疗法等.临床医师需对脉络膜新生血管各种治疗方法 的疗效和安全性有准确、全面的了解,才能取得满意的效果.(中华眼科杂志,2008,44:196-199)

Several important problems in treating neovascularization following age-related macular degeneration

Although great progress have been achieved in treating neovascularization (CNV) secondary to age-related macular degeneration (AMD) in recent years, some essential problem should be considered in gaining better therapeutic results for CNV patients. Firstly we need to know clearly whether the CNV is classic or occult? Secondly we need to understand whether the CNV lesion is actually polypoidal choroidal vasculopathy (PCV) or retinal angiomatous proliferation (RAP)? Thirdly we need to determine to choose photodynamic therapy (PDT) or anti-vascular endothelial growth factor (VEGF) therapy or combination therapy for a individual AMD patient.