实时三维超声心动图对室间隔缺损诊断的实验研究

目的 探讨实时三维超声心动图技术对室间隔缺损定性、定量诊断价值。方法 在离体猪心制备肌部和膜部室间隔缺损22个，应用实时三维超声心动图技术，对室间隔缺损进行多个方位和切面观观察，测量室间隔缺损的横径、纵径和面积，与直视下观察和解剖测值进行比较。结果 所有标本均可获得满意的实时三维图像，能即时显示室间隔缺损的位置、形态、大小、立体空间结构和与毗邻结构的关系，实时三维超声测量值与解剖测值差异无显著性意义，二者具有高度相关性。结论 实时三维超声心动图技术能即时显示室间隔缺损的空间解剖信息，对指导外科手术和介入性治疗具有潜在意义。

A study on qualitative and quantitative diagnosis of ventricular septal defect in vitro by real-time three-dimensional echocardiography

Objective To evaluate the ventricula r septal defect qualitatively and quantitatively by real-time three-dimensional echocardiography (RT-3DE).Methods RT-3DE were performed in 10 pig hearts with 22 ventricular septal defects in multiple orientations and cross sections. The diameters and areas of ventricular septal defects were measured both in RT-3DE and anatomic view. Echo images and parameters derived by RT-3DE were compared with anatomic view. Results Technically satisfactory RT-3DE images were obtained in all preparations. The location, size, morphology, and spatial relationships with surrounding cardiac structure of ventricular septal defects were displayed instantly. No significant differences were found between RT-3DE and anatomic measurements. Conclusions RT-3DE has advantages of instantly displaying the ventricular septal defects in anyplane and has important surgical and interventional implications.