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氟中毒大鼠心电图改变及其硒的影响
引用本文:边建朝,宋术亮.氟中毒大鼠心电图改变及其硒的影响[J].中国地方病防治杂志,1996,11(1):9-10.
作者姓名:边建朝  宋术亮
作者单位:山东省地方病防治研究所 (边建朝,宋术亮,相有章,咸树梅,叶平,杨晓霞),山东省地方病防治研究所(王琳)
摘    要:为观察氟中毒大鼠心电图变化及其Se的影响,两组Wistar大鼠饮用1.58、2.63mg/L高F^-水,另两组鼠饮高F^-水加饲0.025mg/kgSe饲料,在实验前及实验4、8、12个月进描记心电图。结果两组大鼠随摄氟时间延长T波降低,Q-T间期缩短。

关 键 词:氟中毒  心电图    大鼠

EFFECT OF SELENIUM AND CHANGE OF ELECTROCARDIOGRAM OF THE RATS WITH FLUOROSIS
Bian Jianchao Shandong Institute for Prevention and Treatment of Endemic Diseases,Jinan.EFFECT OF SELENIUM AND CHANGE OF ELECTROCARDIOGRAM OF THE RATS WITH FLUOROSIS[J].Chinese Journal of Control of Endemic Disenaces,1996,11(1):9-10.
Authors:Bian Jianchao Shandong Institute for Prevention and Treatment of Endemic Diseases  Jinan
Abstract:In order to observe the effect of selenium and electrocardiogram (ECG) of the rats with fluorosis, 40 wistar rats were fed with normal fodder and high concentration NaF water(1. 58,2. 63 mg/L fluorine,F) ,at the same time,40 wistar rats were fed with selenite fodder(0. 25mg/kg selenium ,Se)and high F water for 12 months,ECG was taken before experiment and after experiment for 4,8, 12 months. The results showed that there were a decrease of T wave and a shortness of Q-T interval in the rats with fluorosis during the different period of fluorosis,an increase of T wave and a prolongation of Q-T interval were observed in the Se supplementation of the rats with fluorosis. The abnormal cause of ECG by F and the mechanism of protection for Se in the rats with fluorosis were discussed in the paper.
Keywords:The rats with fluoroste  Electrocardiogram  Selenium
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