超短波对糖尿病大鼠创面愈合的影响

目的：探讨超短波治疗对糖尿病大鼠创面局部不同时间点溃疡面积、创面愈合率的影响。方法：健康成年雄性SD大鼠90只，随机分为正常组、糖尿病组和超短波组各30只。糖尿病组和超短波组建立糖尿病模型，3组大鼠制作皮肤溃疡模型，正常组、糖尿病组大鼠不进行任何干预，超短波组大鼠行超短波治疗。结果：在伤后第3、7、14及21天，超短波组及糖尿病组不同时间点创面面积均明显大于正常组（ P＜0．05，0．01），超短波组不同时间点创面面积均明显小于糖尿病组（P＜0．01）；超短波组及糖尿病组不同时间点创面愈合率均明显低于正常组（P＜0．05，0．01），超短波组不同时间点创面愈合率明显高于糖尿病组（ P＜0．01）。结论：超短波治疗可促进糖尿病溃疡创面缩短愈合时间，加快愈合速度，为其在促进糖尿病患者创面愈合的治疗中提供理论依据。

Effect of ultrashort wave therapy on wound healing in diabetic rats

Objective:To investigate the effect of ultrashort wave therapy on ulcer wound area and wound healing rate in diabetic rats at different time points.Methods:Ninety healthy adult male SD rats were randomly divided into 3 groups:normal control group (normal group,n=30),diabetic control group (diabetic group,n=30) and ultrashort wave therapy of diabetes group (experimental group,n=30). The diabetic model in rats was established in diabetic group and experimental group.Skin ulcer model was made in all groups.Diabetic group was given no intervention,and experimental group given ultrashort wave treatment.Results:At 3rd,7th,14th,and 21st day after the injury,the ulcer area in experimental group and diabetic group at different time points was significantly larger than in normal group (P<0.05 or <0.01), and that in experimental group was significantly less than in diabetic group (P<0.01).The wound healing rate in experimental group and diabetic group at different time points was significantly lower than in normal group (P<0.05,or <0.01).The wound healing rate in experimental group at different time points was significantly higher than in diabetic group (P<0.01).Conclusion:The ultrashort wave therapy has obvious effect on the diabetic skin ulcer, which may provide a theoretical basis for the ultrashort wave therapy to promote wound healing in diabetic patients.