| 原发性高血压的基因机制-RAAS系统基因多态性 |
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| 引用本文： | 韩姗,丛洪良. 原发性高血压的基因机制-RAAS系统基因多态性[J]. 中国心血管杂志, 2007, 12(2): 138-140 |
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| 作者姓名： | 韩姗 丛洪良 |
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| 作者单位： | 1. 天津市南开大学医学院,天津,300071
2. 天津市胸科医院心内科,天津,300051 |
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| 摘 要： | 原发性高血压(EH)是遗传和环境因素相互作用所致的多因素疾病,对其基因机制的研究有助于从分子水平探讨EH的发病机制.近年来对于EH候选基因多态性的研究逐渐增多,本文即对肾素-血管紧张素-醛固酮系统(RAAS)基因多态性与EH之间的关系的研究进展作一综述.
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| 关 键 词： | 原发性高血压 肾素-血管紧张素-醛固酮系统 基因多态性 |
| 文章编号： | 1007-5410(2007)02-0138-03 |
| 修稿时间： | 2006-09-28 |
Genetic basis of essential hypertension-Gene polymorphisms of renin-angiontensin-aldosterone system |
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| Han Shan,Cong Hong-liang. Genetic basis of essential hypertension-Gene polymorphisms of renin-angiontensin-aldosterone system[J]. Chinese Journal of Cardiovascular Medicine, 2007, 12(2): 138-140 |
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| Authors: | Han Shan Cong Hong-liang |
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| Affiliation: | 1. Medical College of Nankai University, Tianjin 300071; 2. Tianjin Chest Hospital, Tianjin, 300051 ,China |
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| Abstract: | Essential hypertension(EH) is a complex disorder resulting from interaction of genetic and environmental factors.Identify its genetic basis is important in understanding the molecular mechanisms of EH.Recently,more and more candidate genes have been found.This review is to discuss the highlight current studies of the association between the gene polymorphisms of renin-angiontensin-aldosterone system and EH. |
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| Keywords: | Essential hypertension Renin-angiontensin-aldosterone system Gene polymorphism |
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