Intrathecal normal saline without preservative does not have a local anesthetic effect |
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Authors: | Edward Teeple Dianne L. Scott Jawahar N. Ghia |
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Affiliation: | Department of Anesthesiology, University of North Carolina at Chapel Hill, North Carolina Memorial Hospital, Chapel Hill, N.C. 27415 U.S.A. |
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Abstract: | The effects of intrathecally administered normal saline (preservative-free) were studied in patients undergoing differential spinal block anesthesia for evaluation of chronic pain below the waist. The injection of 5 ml saline did not significantly change the sensitivity to pinprick measured in the lower back and both lower extremities. Temperature measurement in both the lower extremities and psycho-galvanic skin reflex did not show evidence of sympathetic block; the psychogalvanic skin reflex was abandoned because of inconsistent results. These findings refute the earlier conclusion of Urban and McKain who found that normal saline acts as a weak local anesthetic when injected intrathecally. We recommend use of normal saline (preservative-free) in 5 ml doses as a placebo for differential spinal block anesthesia. |
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Keywords: | Please send reprint requests to Dr. Edward Teeple Department of Anesthesiology North Carolina Memorial Hospital 204H Chapel Hill N.C. 27415 U.S.A.. |
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