| 依达拉奉对颅脑损伤患者血清胃泌素水平及疗效的影响 |
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| 引用本文： | 高晨,程刚,刘耀明,马宝平,周海燕. 依达拉奉对颅脑损伤患者血清胃泌素水平及疗效的影响[J]. 临床神经病学杂志, 2009, 22(3) |
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| 作者姓名： | 高晨 程刚 刘耀明 马宝平 周海燕 |
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| 作者单位： | 兰州军区兰州总医院安宁分院创伤外科,730070;兰州军区兰州总医院安宁分院创伤外科,730070;兰州军区兰州总医院安宁分院创伤外科,730070;兰州军区兰州总医院安宁分院创伤外科,730070;兰州军区兰州总医院安宁分院创伤外科,730070 |
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| 摘 要： | 目的观察依达拉奉对颅脑损伤患者血清胃泌素水平及疗效的影响。方法60例颅脑损伤患者随机分为依达拉奉组及地塞米松组,并给予相应的治疗。检测治疗后1 d、3 d、5 d、7 d血清胃泌素水平;治疗1个月后依据神经功能缺损程度评分(NDS)及Barthel指数(BI)评价疗效。结果依达拉奉组治疗后第3d血清胃泌素水平开始下降,第5 d、7 d恢复正常;地塞米松组第5 d开始下降,第7 d仍高于正常水平;两组间治疗后3 d、5 d及7 d时血清胃泌素水平差异有统计学意义(P<0.05~0.01)。治疗1个月后依达拉奉组NDS及BI明显优于地塞米松组(均P<0.01);总有效率(83.3%)显著高于地塞米松组(63.3%)(P<0.05)。结论依达拉奉能有效降低颅脑损伤患者血清胃泌素水平,改善神经功能缺损,提高疗效。
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| 关 键 词： | 颅脑损伤 胃泌素 依达拉奉 |
Influence of Edaravone on the level of serum gastrin and efficacy in patients with craniocerebral injury |
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| GAO Chen,CHENG Gang,LIU Yao-ming,et al.. Influence of Edaravone on the level of serum gastrin and efficacy in patients with craniocerebral injury[J]. Journal of Clinical Neurology, 2009, 22(3) |
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| Authors: | GAO Chen CHENG Gang LIU Yao-ming et al. |
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| Affiliation: | GAO Chen,CHENG Gang,LIU Yao-ming,et al.Department of Neurosurgery,General Hospital of Lanzhou Milltary Comm,,Lanzhou 730070,China |
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| Abstract: | Objective To observe the influence of Edaravone on the level of serum gastrin and efficacy in patients with craniocerebral injury.Methods 60 patients with craniocerebral injury were randomly divided into Edaravone group(30 cases) and Dexamethasone group(30 cases).Then each group received corresponding treatment.The level of serum gastrin was detected at 1st d,3rd d,5th d and 7th d after treatment.The curative effect was evaluated based on the neuroligical deficit score(NDS) and Barthel index(BI) one month a... |
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| Keywords: | craniocerebral injury gastrin Edaravone |
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