| 常规机械通气与高频振荡通气在胎粪吸入综合征中的应用 |
| |
| 引用本文： | 丁异熠,唐红平,王彦杰.常规机械通气与高频振荡通气在胎粪吸入综合征中的应用[J].医学临床研究,2012(11):2087-2089. |
| |
| 作者姓名： | 丁异熠 唐红平 王彦杰 |
| |
| 作者单位： | [1]湖南省常德市第一人民医院,湖南常德415003 [2]广东省外语艺术职业学院医院,广东广州510640 |
| |
| 摘 要： | 【目的】评价常规机械通气（CMV）与高频振荡通气（HFOV）治疗新生儿重症胎粪吸入综合征（MAS）的疗效。【方法】对本院2008年9月至2011年6月83例重症MAS新生儿予CMV或HFOV治疗。观察比较CMV与HFOV治疗前后肺功能变化及病情转归。【结果】CMV治疗组与HFOV治疗组动脉氧分压（Pa02）分别由治疗前的（47．95土14．44）mmHg、（62．16±23．03）mmHg上升为（82．84±19．82）mmHg、（81．69士23．84）mmHg（P〈0．05）。氧合指数（Pa02／Fi02）分别由治疗前的（218．30±70．98）（173．59±74．44）增加到（275．52±68．40）、（237．02±89．22）（P〈0．05）；动脉二氧化碳分压（PaC02）分剐由（51．42±12．43）mmHg、（48．95±12．11）mmHg下降到（40．11±7．87）mmHg、（41．89土12．69）mmHg（P〈0．05）。在颅内出血并发症中CMV治疗组高于HFOV治疗组（P〈0．05）。【结论】CMV与HFOV用于新生儿重症MAS疗效好，均能较快改善肺氧合功能，改善预后，HFOV在重症MAS应用中可作为CMV应用失败的补救方法，并发症较低。
|
| 关 键 词： | 胎粪吸入 治疗 综合征 呼吸 人工 |
Application of Conventional Mechanical Ventilation and High-frequency Oscillatory Ventilationin Pediatric Patients with Meconium Aspiration Syndrome |
| |
| Institution: | DING Yi-Yi, TANG Hong-ping, WAMG Yan-Jie ( Department of Neonatology, First People＇s Hospital of Changde City, Hunan 415003, China ) |
| |
| Abstract: | Objective]To evaluate the efficacy of conventional mechanical ventilation（CMV） and high-fre- quency oscillation ventilation（HFOV） for the treatment of neonates with severe meconium aspiration syndrome （MAS）. Methods]A total of 83 neonates with severe MAS received CMV or HFOV treatment. The change of pulmonary function and the prognosis were observed before and after CMV or HFOV treatment. Results] Arterial oxygen pressure（PaO2） in CMV treatment group and HFOV treatment group increased from （47.95 ±14.44）mmHg and （62.16±23.03）mmHg to （82.84±19.82）mmHg and （81.69±23.84）mmHg（ P 〈0.05） respectively, and oxygenation index（PaO2/FiO2 ） increased from （218. 30 ± 70. 98） and （173. 59± 74.44） to （275.52±68.40） and （237.02±89.22）（ P 〈0.05） respectively, and partial pressure of carbon di- oxide in arterial blood（PaCO2） decreased from （51.42±12.43）mmHg and （48.95±12.11）mmHg to （40.11 ± 7.87）mmHg and （41.89± 12.69）mmHg（ P 〈0.05） respectively. The incidence of intracranial hemorrhage in CMV treatment group was higher than that in HFOV treatment group（ P 〈0.05）. Conclusion]CMV and HFOV for the treatment of neonates with severe MAS has good efficacy, and both of them can improve pulmo- nary oxygenation function quickly and the prognosis. HFOV applied in severe MAS can be used as a remedy method for the failure of CMV treatment, and has a lower incidence of complications. |
| |
| Keywords: | meconium aspiration/TH syndrome respiration artificial |
| 本文献已被 维普 等数据库收录！ |
