运城市2001-2004年再生障碍性贫血流行病学调查

目的 掌握运城市再生障碍性贫血发病率及分布情况.方法 对2001-2004年再生障碍性贫血发病率、分布、病因进行回顾性调查分析.结果 运城市2001-2004年再生障碍性贫血发病率为0.59/10万,标化率为0.59/10万;男性发病率0.70/10万,标化率0.67/10万;女性发病率0.49/10万,标化率0.49/10万;男性发病率高于女性(1.37:1).再生障碍性贫血在工业经济发展较快的盐湖、河津、闻喜等县(市、区)发病率明显高于工业发展较慢的稷山、平陆、夏县等县.不同职业再生障碍性贫血发病率分别为工人>农民>学生>儿童>干部.男女再生障碍性贫血发病率随年龄增长均出现两个高峰.男性第一个高峰在10～24岁段,55_69岁段出现第二个高峰;女性第一个高峰在20～34岁段,45～64岁段出现第二个高峰.急性再生障碍性贫血发病率为0.15/10万;慢性再生障碍性贫血发病率为0.44/10万;急慢性发病率比为0.34:1.男性急性再生障碍性贫血发病率为0.16/10万,男性慢性再生障碍性贫血发病率为0.52/10万;女性急性再生障碍性贫血发病率为0.15/10万,女性慢性再生障碍性贫血发病率为0.35/10万.结论 运城市再生障碍性贫血发病率较全国为低;男性再生障碍性贫血发病率高于女性;男女再生障碍性贫血随年龄变化均出现2个高峰;无论男女,慢性再生障碍性贫血发病率均高于急性再生障碍性贫血发病率.不同职业人群中,工人再生障碍性贫血发病率最高,干部发病率最低;再生障碍性贫血在环境污染较严重县(市、区)发病率较高.

An epidemiological investigation of aplastic anemia from 2001 to 2004 in Yuncheng

Objective To investigate the incidence and distribution of aplastic anemia in the city of Yuncheng.Methods The incidence,distribution and cause of desease of aplastic anemia had been retrospectively studied and analysised from 2001 to 2004.Results Among the 0.59/100 000 aplastic anemia incidence rate between 2001 and 2004,0.70/100 000 was male,0.49/100 000 was female.Among the 0.59/100 000 aplastic anemia standardized rate between 2001 and 2004,0.67/100 000 was male,0.49/100 000 was female.In short,male was more than female from incidence rate.According to investigation,the incidence of aplastic anemia in developed industrial area(Saline Lake,Hejin,Wenxi and so on) was significantly higher than that of industrial developing area(Jishan,Pinglu,Xia county and so on).Different occupation had different incidence rate such as workers>famer>student>children>manager.Grown up with age,there were two peaks both male and female in aplastic anemia incidence rate.Male′s first peak appeared(10-24 years old),second peak(55-69 years old).Female′ first peak appeared(20-34 years old),second peak(45-64 years old).Incidence rate of acute aplastic anemia was 0.15/100 000 while incidence rate of chronic aplastic anemia incidence was 0.44/100 000.Incidence ratio of acute and chronic aplastic anemia was 0.34∶1.Acute aplastic anemia incidence for male was 0.16/100 000,while chronic was 0.52/100 000.Acute aplastic anemia incidence for female 0.15/100 000 while chronic 0.35/100 000.Conclusion The incidence rate in the city of Yuncheng is lower than the other city in China.Male is higher than women in aplastic anemia incidence rate.There are two peaks with age changing both male and female in incidence rate.The incidence of chronic aplastic anemia is higher than that of acute aplastic anemia.For different groups,the highest incidence is from workers,while cadre with the minimum morbidity rate.Aplastic anemia in the county(city or area) which environmental pollution was serious had a high incidence.