Abstract: | Clinico-instrumental and hormonal investigation of 31 patients with diffuse euthyroid goiter was conducted. To test the efficacy of indometacin as an antigoitrogenic drug, these patients were given it for 2 mos. Combined examination of the patients showed the absence of thyroid decrease and changes in thyroid function against a background of indometacin monotherapy. The results point out to the fact that the drug should not be used for elimination of thyroid hyperplasia in persons with diffuse euthyroid goiter. |