高频电刀联合阴道镜诊治宫颈病变临床观察

目的 探讨高频环形电切术(LEEP)联合阴道镜在治疗宫颈病变的作用.方法 对116例宫颈上皮内瘤样病变(CIN)患者接受LEEP术治疗,进行随机对照研究,其中研究组60例,在进行LEEP术前先行阴道镜检查明确CIN的解剖学位置及其分布特征.对照组56例,在进行LEEP术前,宫颈表面涂复方碘溶液确定CIN的分布.术后1月内,3个月,6个月进行随访.比较两组手术中出血量及手术时间,术后切缘未净发生率,随访发现宫颈CIN发生情况.结果 研究组术后切缘未净发生率6.67％ (4/60),低于对照组的17.86％ (10/56),(P=0.018)；两组手术时间及手术中出血量无统计学意义(P＞0.05).结论 阴道镜定位下高频环形电切除术治疗宫颈病变有效减低切缘残留发生率.

Clinical observation on loop electrosurgical excision procefure and colposcope in diagnosis and treatment for cevical intraepithelial neoplasia

Objective To study the effect of loop electrosurgical excision procedure（LEEP） and colposcope in diagnosis and treatment for cervical intraepithelial neoplasia.Methods A prospective randomized control trail was performed in 116 cervical in traepithelial neoplasia（CIN）patients wederwent LEEP.In 60 patients in the study group,the colposcope definitude locality and distributing of CIN before LEEP.In 56 patients the control group,spread Iodin solution on cervical definitude locality and distributing of CIN before LEEP.Then,follow-up was performed postoperatively in 1,3,6 months respectively.The operation time,the bleeding volume,the rate of residual were compared between the two groups,follow-up CIN.Results The rate of residual in the study group（4/60）6.67% was lower than that in the control group（10/56）17.86%.There was statistical difference between them（P=0.018）.There was no statistical difference between them in the operation time and the bleeding volume（P＞0.05）.Conclusion With colposcope,Can reduce the rate of residual.