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Noise benefit in prepulse inhibition of the acoustic startle reflex
Authors:Erik Pålsson  Göran Söderlund  Daniel Klamer  Filip Bergquist
Affiliation:(1) Department of Pharmacology, Institute of Neuroscience and Physiology, The Sahlgrenska Academy, University of Gothenburg, Box 400, 405 30 Gothenburg, Sweden;(2) Department of Linguistics, Stockholm University, 106 91 Stockholm, Sweden;(3) Clinical Neuroscience and Rehabiliation, Institute of Neuroscience and Physiology, The Sahlgrenska Academy, University of Gothenburg, Box 400, 405 30 Gothenburg, Sweden;
Abstract:

Rationale  

Under some conditions, external sensory noise enhances cognitive functions, a phenomenon possibly involving stochastic resonance and/or enhanced central dopamine transmission. Prepulse inhibition (PPI) of the startle reflex is a robust measure of sensorimotor gating and can be modulated by activity in the cortex and basal ganglia, including the central dopamine pathways.
Keywords:
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