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老年性白内障患者血清中一氧化氮和总超氧化物歧化酶测定及意义
引用本文:朱佩英,薛晓芳.老年性白内障患者血清中一氧化氮和总超氧化物歧化酶测定及意义[J].上海预防医学,2005,17(8):377-378.
作者姓名:朱佩英  薛晓芳
作者单位:上海市第八人民医院检验科,上海,200233;上海市第八人民医院检验科,上海,200233
摘    要:目的]探索一氧化氮和总超氧化物歧化酶(T-SOD)与老年性白内障(SC)发病的关系。方法]应用硝酸盐还原法和黄嘌呤氧化酶法分别检测128例SC患者以及100例健康老年人血清NO含量和T-SOD活力。结果]SC患者血清NO含量较正常对照组显著升高(P<0.01);SC患者血清SOD水平较正常对照组显著降低(P<0.01)。结论]血清NO含量升高、血清SOD活力降低与老年性白内障发病有联系。

关 键 词:一氧化氮  总超氧化物歧化酶  老年性白内障
文章编号:1004-9231(2005)08-0377-02
收稿时间:02 20 2005 12:00AM
修稿时间:2005年2月20日

Significance and determination of nitric oxide and total superoxide dismutase concentration in serum of senile cataract patients
ZHU Pei-ying,XUE Xiao-fang.Significance and determination of nitric oxide and total superoxide dismutase concentration in serum of senile cataract patients[J].Shanghai Journal of Preventive Medicine,2005,17(8):377-378.
Authors:ZHU Pei-ying  XUE Xiao-fang
Abstract:Objective]To investigate the relationship of nitric oxide (NO)and superoxide dismutase (SOD) with the pathogenesis of cataract.Methods]Using nitric acid reductase method and xanthine oxidase method,the levels of NO and T-SOD in sera obtained from 128 senile cataract patients and 100 senile normal volunteers were determined.Results]The levels of NO in serum of senile cataract group were significantly higher than those of control group (P<0.01).The levels of SOD in serum of senile cataract patients were much lower than those of control group (P<0.01). Conclusion]The levels of NO and T-SOD are related to the pathogenesis of catarat.
Keywords:Nitie oxide  Total superoxide dismutase  Senile cataract patients
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